ATI RN
ATI Practice Exam Pharmacology The Hematologic System Questions
Question 1 of 5
A female patient needs a whole blood transfusion. In order for transfusion services (the blood bank) to prepare the correct product a sample of the patient's blood must be obtained for:
Correct Answer: B
Rationale: Before administering a whole blood transfusion to a patient, it is crucial for the transfusion services to determine the patient's blood type and perform a crossmatch with the donor blood to ensure compatibility. The blood type (e.g., ABO and Rh) of the patient must be identified to select compatible donor blood. A crossmatch is performed to further confirm compatibility and prevent adverse reactions, such as hemolytic transfusion reactions, which can occur when incompatible blood components are transfused. This process helps ensure the safety and efficacy of the transfusion for the patient. A complete blood count and differential, blood culture and sensitivity, and antibody screening are important tests in other clinical contexts but are not essential for preparing a whole blood transfusion.
Question 2 of 5
Following ingestion, a drug crosses a membrane from an area of higher concentration to an area of lower concentration. This is an example of
Correct Answer: C
Rationale: Diffusion moves drugs passively from high to low concentration across membranes, like oral absorption, a pharmacokinetic staple. Active transport uses energy against gradients. Osmosis is water-specific. Metabolism alters drugs chemically. Diffusion fits, driving initial uptake.
Question 3 of 5
Three days after a patient's total colectomy and ileostomy, he has a nasogastric tube for continuous suction and a Foley catheter for continuous drainage. The night nurse reports a high output from the ileostomy. The patient's pulse is irregular, and he reports leg weakness. Based on this situation, the nurse would correctly suspect what type of imbalance?
Correct Answer: A
Rationale: The patient's symptoms of irregular pulse and leg weakness, along with high ileostomy output, suggest hypokalemia. High ileostomy output can lead to excessive loss of potassium, a key electrolyte responsible for muscle and nerve function. Hypokalemia can cause muscle weakness and cardiac arrhythmias, which align with the patient's symptoms. Hyperkalemia (
B) would typically cause muscle cramps and cardiac abnormalities like peaked T-waves, not weakness. Hyponatremia (
C) and hypercalcemia (
D) do not typically present with these specific symptoms.
Question 4 of 5
The following are examples of prodrugs:
Correct Answer: A
Rationale: Levodopa is a prodrug converted to dopamine in the brain, bypassing the blood-brain barrier. Prodrugs are inactive compounds metabolized into active drugs in the body.
Question 5 of 5
A client has been using sildenafil (Viagra) for several months. Which client reports would the nurse interpret as an adverse effect of this medication?
Correct Answer: A
Rationale: Sildenafil (Viagra) commonly causes nasal congestion due to vasodilation affecting nasal blood vessels, a frequent adverse effect tied to its mechanism. Earache isn't a recognized side effect-sildenafil targets vascular smooth muscle, not auditory systems. Blurry vision occurs from PDE-6 inhibition in the retina, another known issue. Priapism, a sustained erection, is a rare but serious risk requiring urgent care. Nasal congestion stands out as a typical, manageable effect, reflecting sildenafil's systemic vasodilatory impact, distinct from less common visual or emergent issues, and aligns with patient reports needing monitoring.