ATI RN
Pharmacology Test Bank Questions
Question 1 of 5
Serotonin release stimulates vomiting following chemotherapy. Therefore, serotonin antagonists are effective in preventing and treating nausea and vomiting related to chemotherapy. An example of an effective serotonin antagonist antiemetic is:
Correct Answer: A
Rationale: Ondansetron is an example of a serotonin antagonist antiemetic that is effective in preventing and treating nausea and vomiting related to chemotherapy. It works by blocking serotonin receptors both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. By antagonizing serotonin, ondansetron helps to reduce the emetic response triggered by chemotherapy, leading to improved control of nausea and vomiting. In contrast, the other options (B. fluoxetine, C., D. paroxetine, E. sertraline) are selective serotonin reuptake inhibitors (SSRIs) used mainly for the treatment of depression and anxiety disorders, and they do not have the same antiemetic properties as ondansetron.
Question 2 of 5
A patient who has been taking antihypertensive drugs for a few months complains of having a persistent dry cough. The nurse knows that this cough is an adverse effect of which class of antihypertensive drugs?
Correct Answer: B
Rationale: The persistent dry cough mentioned by the patient is a well-known adverse effect of ACE inhibitors. This side effect is due to the accumulation of bradykinin in the lungs, leading to irritation and stimulation of cough receptors. If a patient taking an ACE inhibitor develops a persistent dry cough, it is essential to notify the healthcare provider to consider alternative antihypertensive medications to manage the hypertension effectively without causing this bothersome side effect.
Question 3 of 5
When monitoring a patient who is taking hydrochlorothiazide (HydroDIURIL), the nurse notes that which drug is most likely to cause a severe interaction with the diuretic?
Correct Answer: A
Rationale: Digitalis (e.g., Digoxin) and hydrochlorothiazide can cause a severe interaction because hydrochlorothiazide can reduce potassium levels in the body. Low potassium levels (hypokalemia) can increase the risk of digitalis toxicity, leading to dangerous effects on the heart.
Therefore, patients taking hydrochlorothiazide along with digitalis need close monitoring of their potassium levels and potential adjustments to their digitalis therapy. It is important to communicate this risk to the healthcare team to ensure patient safety.
Question 4 of 5
The nurse is preparing for a community education program on hypertension. Which of these parameters determine the regulation of arterial blood pressure?
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
When monitoring a patient who has diabetes and is receiving a carbonic anhydrase inhibitor for edema, the nurse will monitor for which possible adverse effect?
Correct Answer: B
Rationale: Carbonic anhydrase inhibitors are a class of medications used to treat edema by decreasing the production of aqueous humor in the eye and reducing fluid in the body. One common side effect of carbonic anhydrase inhibitors is metabolic acidosis, which can lead to increased blood glucose levels in patients with diabetes. The medication may interfere with the body's ability to regulate blood glucose levels, leading to elevated blood glucose.
Therefore, when monitoring a patient with diabetes who is receiving a carbonic anhydrase inhibitor, the nurse should closely monitor for signs of elevated blood glucose levels to prevent potential complications.