ATI RN
Pharmacology Test Bank Questions
Question 1 of 5
The female client has a fungal infection and will receive nystatin (Mycostatin). What assessment data is critical for the nurse to review prior to administering this medication?
Correct Answer: C
Rationale: Nystatin is an antifungal medication used to treat fungal infections, such as candidiasis. Before administration, assessing whether the client could be pregnant is critical because nystatin's safety in pregnancy is not fully established (Category
C), meaning potential risks to the fetus cannot be ruled out without further evaluation. This makes pregnancy status a key safety consideration to prevent harm to an unborn child, outweighing other factors in urgency. The type of diet or amount of fat might influence general health or drug absorption minimally but isn't directly critical to nystatin's administration. Height and weight could affect dosing in some medications, but nystatin's dosing is typically standard and not weight-based for most fungal infections. Thus, confirming pregnancy status ensures the drug's safety profile aligns with the client's condition, making choice C the most critical assessment data to review prior to administration.
Question 2 of 5
The patient has been prescribed dextromethorphan (Delsym). What medication information should the nurse provide?
Correct Answer: D
Rationale: Dextromethorphan with alcohol risks slurred speech . Smoking and timing are off. D ensures safety, making it key.
Question 3 of 5
The following are metabolized by enzymes in the hepatic smooth endoplasmic reticulum:
Correct Answer: C
Rationale: Metoprolol is metabolized primarily by hepatic enzymes in the smooth endoplasmic reticulum via CYP450 pathways.
Question 4 of 5
A patient who has been taking antihypertensive drugs for a few months complains of having a persistent dry cough. The nurse knows that this cough is an adverse effect of which class of antihypertensive drugs?
Correct Answer: B
Rationale: The persistent dry cough mentioned by the patient is a well-known adverse effect of ACE inhibitors. This side effect is due to the accumulation of bradykinin in the lungs, leading to irritation and stimulation of cough receptors. If a patient taking an ACE inhibitor develops a persistent dry cough, it is essential to notify the healthcare provider to consider alternative antihypertensive medications to manage the hypertension effectively without causing this bothersome side effect.
Question 5 of 5
Serotonin release stimulates vomiting following chemotherapy. Therefore, serotonin antagonists are effective in preventing and treating nausea and vomiting related to chemotherapy. An example of an effective serotonin antagonist antiemetic is:
Correct Answer: A
Rationale: Ondansetron is an example of a serotonin antagonist antiemetic that is effective in preventing and treating nausea and vomiting related to chemotherapy. It works by blocking serotonin receptors both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone. By antagonizing serotonin, ondansetron helps to reduce the emetic response triggered by chemotherapy, leading to improved control of nausea and vomiting. In contrast, the other options (B. fluoxetine, C., D. paroxetine, E. sertraline) are selective serotonin reuptake inhibitors (SSRIs) used mainly for the treatment of depression and anxiety disorders, and they do not have the same antiemetic properties as ondansetron.