Correct Answer: A

Rationale: One potential adverse effect of antihypertensive drugs, particularly beta-blockers and diuretics, is impotence. Antihypertensive medications can affect sexual function in males by causing erectile dysfunction or impotence due to their mechanism of action on blood vessels and circulation. It is important for the nurse to inform the patient about this possible side effect so that appropriate management strategies or alternative treatment options can be discussed. Impotence can have a significant impact on a patient's quality of life and adherence to medication, so open communication and education are essential in managing this issue.

Correct Answer: D

Rationale: Spironolactone is a potassium-sparing diuretic that works by promoting potassium retention in the body.
Therefore, patients taking spironolactone are at a higher risk of developing hyperkalemia, which is an elevated level of potassium in the blood. Hyperkalemia can lead to serious complications such as cardiac arrhythmias, muscle weakness, and even cardiac arrest. It is important for the nurse to monitor patients on spironolactone for signs and symptoms of hyperkalemia, such as weakness, numbness, tingling, or an irregular heartbeat. Other diuretics like hydrochlorothiazide (
A), furosemide (
B), and acetazolamide (
C) do not typically cause hyperkalemia as they work to decrease potassium levels in the body.

Correct Answer: D

Rationale: Clopidogrel is a drug that has a therapeutic effect in preventing thromboembolic events. It is an antiplatelet agent that works by inhibiting platelet aggregation, thus reducing the risk of blood clot formation. Clopidogrel is commonly used in patients at risk for cardiovascular events such as heart attacks and strokes. Warfarin is an anticoagulant medication that also helps prevent blood clots, but it works by a different mechanism than clopidogrel. Amlodipine is a calcium channel blocker used to treat hypertension and angina, while nitroglycerine is a vasodilator used in the treatment of angina.

Correct Answer: D

Rationale: Local anesthetic drugs typically contain an aromatic residue linked to an amine group, giving them a weak base property. They are usually soluble in water when converted into soluble salts, most commonly in the form of hydrochlorides. Additionally, local anesthetics are classified based on their chemical structure, with the key component being an ester or amide linkage.
Therefore, choice D, which suggests an acidic group in the structure of a local anesthetic drug, is not accurate.

Correct Answer: B

Rationale: Lethal dose (e.g., LD50) from research guides safe dosing by showing toxicity thresholds, reassuring the patient it informs, not dictates, prescription. It's not just research trivia-doctors use it indirectly. Side effect watching doesn't explain it. Deferring to the doctor avoids education. Research value ties to safety, clarifying its relevance.