ATI RN
ATI Capstone Pharmacology Assessment 2 Questions
Question 1 of 5
A client is prescribed fluoxetine (Prozac) for depression. Which statement by the client indicates a need for further teaching?
Correct Answer: B
Rationale: Fluoxetine, an SSRI, treats depression but interacts with alcohol, worsening sedation or mood , indicating a teaching gap'clients must avoid it. Feeling better in weeks aligns with SSRI onset. Reporting suicidal thoughts is critical due to early risk. Morning dosing prevents insomnia. Drinking wine risks treatment failure or safety issues, critical in depression where stability is fragile. Further teaching must clarify this interaction, ensuring fluoxetine's efficacy and client well-being, making B the statement needing correction.
Question 2 of 5
The following drugs are reversible competitive antagonists:
Correct Answer: D
Rationale: Naloxone is a reversible competitive antagonist at opioid receptors, reversing opioid effects by competing for binding without activating the receptor.
Question 3 of 5
A patient undergoing chemotherapy for breast cancer asks why she is not receiving trastuzumab like her sister. Which response by the nurse is correct?
Correct Answer: D
Rationale: Trastuzumab is a targeted therapy used specifically for HER2-positive breast cancer. If the patient's cancer cells do not overexpress the HER2 receptor, trastuzumab will not be effective. The decision to use targeted therapy is based on the molecular characteristics of the tumor, not the patient's age, insurance coverage, or estrogen receptor status. The nurse should explain that targeted therapies are tailored to the specific biology of the cancer, and trastuzumab is only appropriate for HER2-positive tumors.
Question 4 of 5
The following drugs are considered safe in lactation:
Correct Answer: D
Rationale: These drugs are generally safe during breastfeeding, with minimal risk of transfer to the infant.
Question 5 of 5
If a bacteria were susceptible to both penicillin and erythromycin, then it would not be appropriate to treat the patients with both antibiotics at the same time because:
Correct Answer: A
Rationale: Penicillin is inactivated by erythromycin. Penicillin is a beta-lactam antibiotic which acts by inhibiting cell wall synthesis in bacteria. However, erythromycin is a macrolide antibiotic which can inactivate beta-lactam antibiotics like penicillin. When given together, erythromycin can inactivate penicillin, reducing its efficacy and potentially leading to treatment failure.
Therefore, it is not appropriate to use both penicillin and erythromycin simultaneously to treat a bacterial infection.