ATI RN
Test Bank Pharmacology Questions
Question 1 of 5
The nurse is aware that efficient absorption of calcium is assisted by
Correct Answer: D
Rationale: Calcium absorption in the small intestine relies heavily on vitamin D, which enhances the process by increasing the expression of calcium-binding proteins and improving gut uptake efficiency. Without adequate vitamin D, calcium absorption drops significantly, leading to potential bone health issues like osteoporosis or osteomalacia. Intrinsic factor, produced in the stomach, is critical for vitamin B12 absorption, not calcium, as it binds B12 for uptake in the ileum. Coenzymes, while involved in metabolic reactions, don't directly facilitate calcium absorption; their role is broader and unrelated to this specific process. Phosphorus, an abundant mineral, works with calcium in bone formation but doesn't enhance its absorption-in fact, excessive phosphorus can compete with calcium. Vitamin D's active form, calcitriol, regulates calcium levels by promoting its transport across intestinal cells, making it indispensable for maintaining skeletal integrity. This mechanism underscores why vitamin D deficiency impairs calcium utilization, distinguishing it from the other options, which lack a direct link to absorption efficiency.
Question 2 of 5
The following drugs are contraindicated in asthma:
Correct Answer: B
Rationale: Propranolol, a nonselective beta-blocker, can exacerbate asthma symptoms by causing bronchoconstriction.
Question 3 of 5
Which of the following is the antidote for Heparin?
Correct Answer: A
Rationale: Protamine sulfate is the antidote for Heparin. Heparin is an anticoagulant medication that works by inhibiting the clotting factors in the blood. In cases of Heparin overdose or when there is a need to reverse its anticoagulant effects quickly, protamine sulfate can be administered. Protamine sulfate binds to Heparin and neutralizes its anticoagulant effects, making it an effective antidote. It is important to administer the antidote under the guidance of a healthcare professional to prevent any adverse reactions.
Question 4 of 5
A patient has a digoxin level of 1.1 ng/mL. Which interpretation by the nurse is correct?
Correct Answer: A
Rationale: The therapeutic range for digoxin levels is typically between 0.8-2.0 ng/mL. A digoxin level of 1.1 ng/mL falls below the lower end of the therapeutic range, indicating that it is below the level considered effective for therapeutic benefits.
Therefore, the correct interpretation by the nurse is that it is below the therapeutic level.
Question 5 of 5
A client with gout is prescribed allopurinol (Zyloprim). Which laboratory value should the nurse monitor?
Correct Answer: A
Rationale: Allopurinol reduces uric acid production, treating gout by inhibiting xanthine oxidase. Monitoring serum uric acid tracks efficacy, ensuring levels drop (normal: 3.5-7.2 mg/dL) to prevent flares. BUN reflects kidney function, relevant but secondary unless damage exists. White blood cells and platelets aren't directly affected unless hypersensitivity occurs (rare). Uric acid is the therapeutic target, aligning with allopurinol's mechanism, critical in gout where hyperuricemia drives symptoms. Regular checks confirm treatment success, guiding dose adjustments, making A the key value to monitor.