ATI RN
Practice ATI B Exam Pharmacology Questions
Question 1 of 5
A patient who has been diagnosed with social anxiety disorder will begin taking venlafaxine(Effexor). The nurse who performs a medication and dietary history will be concerned about ingestion of which substance or drug?
Correct Answer: D
Rationale: St. John's wort is an herbal supplement known to interact with many medications, including venlafaxine (Effexor). It can reduce the effectiveness of venlafaxine by increasing its metabolism and clearance from the body, potentially leading to decreased therapeutic effects.
Therefore, patients taking venlafaxine for social anxiety disorder should be advised to avoid St. John's wort to prevent any negative interactions and ensure the medication works effectively. It is essential for the nurse to inquire about the use of St. John's wort during the medication and dietary history assessment to prevent such interactions.
Question 2 of 5
A patient says, 'I have such bad seasonal allergies. Is there anything I can take to keep them from happening?' What information should the nurse provide?
Correct Answer: C
Rationale: Preventing seasonal allergies involves blocking histamine (antihistamines, choice
A), reducing inflammation (corticosteroids, choice
B), or stabilizing mast cells . Mast cell stabilizers (e.g., cromolyn) prevent histamine release, a proactive approach. Decongestants relieve symptoms, not prevent.
Choice C highlights a preventive mechanism, key for allergy management education.
Question 3 of 5
A patient comes to the ER with a painful stab wound. The ER resident administers pentazocine for the pain. Soon after administration the patient experiences sweating, restlessness, and an increase in pain sensations. What is the most likely explanation for his symptoms?
Correct Answer: B
Rationale: Pentazocine, a mixed opioid agonist-antagonist, acts as a kappa receptor agonist and a partial mu receptor agonist, providing analgesia in opioid-naive patients. However, in a heroin addict with high mu receptor tolerance, pentazocine's partial antagonism at mu receptors can displace full agonists like heroin, precipitating withdrawal symptoms—sweating, restlessness, and heightened pain perception.
Tolerance to pentazocine itself wouldn't typically increase pain; it would reduce efficacy. Pentazocine is an effective analgesic in appropriate contexts, so ineffectiveness isn't the issue. Incorrect dosing might alter efficacy or toxicity but wouldn't specifically cause this withdrawal-like reaction. The patient's history of heroin use explains this response, as pentazocine's antagonist properties disrupt the opioid equilibrium, unmasking withdrawal in a dependent individual.
Question 4 of 5
Select all when taking Iron Supplements.
Correct Answer: A
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 5 of 5
A patient is hypokalemic and will be receiving IV potassium. The patient is not on a heart monitor. How should the nurse administer the potassium replacement?
Correct Answer: C
Rationale: When administering IV potassium to a hypokalemic patient who is not on a heart monitor, it's important to ensure a controlled rate of infusion to prevent dangerous cardiac arrhythmias. The recommended maximum rate for IV potassium replacement in this scenario is typically no more than 20 mEq/hour. Faster administration rates can increase the risk of hyperkalemia and potentially lead to serious cardiac complications. Monitoring the patient closely for signs of hyperkalemia such as ECG changes or muscle weakness is also crucial during potassium replacement therapy.