ATI RN
Intro to Pharmacology ATI Questions
Question 1 of 5
What is the therapeutic use for Lithium?
Correct Answer: B
Rationale: Lithium is primarily used in the treatment of bipolar disorder to decrease the incidence of acute manic episodes. It helps to stabilize mood and prevent the extreme highs (manic episodes) associated with bipolar disorder. Lithium is not used to decrease blood pressure, seizure activity, or increase urinary output.
Question 2 of 5
The following drugs undergo phase II metabolism by hepatic acetylation enzymes (N-acetyltransferases):
Correct Answer: D
Rationale: Isoniazid undergoes phase II acetylation via hepatic N-acetyltransferases, and the rate of metabolism can vary between slow and fast acetylators.
Question 3 of 5
Combination chemotherapy is used in the treatment of cancer because:
Correct Answer: A
Rationale: Combination chemotherapy is used to target cancer cells through multiple mechanisms, reducing the likelihood of resistance. Single-agent therapy often leads to the development of resistant cell lines, as cancer cells can adapt to the drug. By using a combination of drugs with different mechanisms of action, the treatment can more effectively kill cancer cells and prevent resistance. While two drugs may increase efficacy, the primary rationale is to overcome resistance. Larger doses of single agents are not the main reason for combination therapy.
Question 4 of 5
Furosemide (Lasix) is prescribed for a patient who is about to be discharged, and the nurse provides instructions to the patient about the medication. Which statement by the nurse is correct?
Correct Answer: D
Rationale: The correct statement by the nurse is D. "Be sure to change positions slowly and rise slowly after sitting or lying so as to prevent dizziness and possible fainting because of blood pressure changes." This instruction is important for patients taking furosemide (Lasix) because this medication can cause changes in blood pressure, especially when changing positions quickly. By rising slowly, the patient can minimize the risk of dizziness or fainting. This precaution is crucial to ensure patient safety while taking furosemide.
Question 5 of 5
The nurse is creating a plan of care for a patient with a new diagnosis of hypertension. Which is a potential nursing diagnosis for the patient taking antihypertensive medications?
Correct Answer: B
Rationale: Sexual dysfunction is a potential nursing diagnosis for a patient taking antihypertensive medications because certain classes of antihypertensive drugs, such as beta blockers and thiazide diuretics, have been known to cause sexual side effects. These effects may include erectile dysfunction in men and decreased libido or altered menstrual cycles in women. It is important for nurses to assess and address any sexual dysfunction concerns in patients on antihypertensive medications to improve quality of life and adherence to treatment. Diarrhea, urge urinary incontinence, and impaired memory are not typically associated with antihypertensive medications and would not be as relevant in this situation.