ATI RN
ATI PN Pharmacology Proctored Exam 2023 Questions
Question 1 of 5
What is the pharmacological class of Metformin?
Correct Answer: C
Rationale: Metformin belongs to the pharmacological class known as biguanides. Biguanides are a group of oral medications commonly used to treat type 2 diabetes by lowering blood sugar levels. Metformin works primarily by decreasing the production of glucose in the liver while also increasing the sensitivity of muscle cells to insulin. This class of drugs does not stimulate insulin release from the pancreas like sulfonylureas and meglitinides but rather works by targeting the liver and improving insulin sensitivity in peripheral tissues. The main pharmacological effect of metformin is to reduce hepatic glucose output, which helps to control blood glucose levels in individuals with type 2 diabetes.
Question 2 of 5
A 26-year-old alcoholic man is trying to quit drinking. He complains that previous attempts have been thwarted by intense anxiety and insomnia that occur in the absence of alcohol. These symptoms disappear when he resumes alcohol use. Which of the following medications will reduce this patient's anxiety and insomnia from his alcohol withdrawal?
Correct Answer: C
Rationale: Alcohol withdrawal (anxiety, insomnia) responds to benzodiazepines, but Methadone is listed-likely a typo for a benzo like lorazepam assumed. Acamprosate reduces cravings. Disulfiram deters drinking. Naltrexone (E) blocks reward. Methanol is toxic. Benzos calm withdrawal.
Question 3 of 5
It is defined as the fraction of drug absorbed by the body
Correct Answer: A
Rationale: Bioavailability is defined as the fraction of drug that reaches systemic circulation in an unchanged form after administration. It is a crucial pharmacokinetic parameter that reflects the amount and rate of drug absorption. Bioavailability can be influenced by various factors such as the route of administration, drug formulation, and first-pass metabolism. Monitoring bioavailability is important in determining the efficacy and dosage requirements of a drug.
Question 4 of 5
Three days after a patient's total colectomy and ileostomy, he has a nasogastric tube for continuous suction and a Foley catheter for continuous drainage. The night nurse reports a high output from the ileostomy. The patient's pulse is irregular, and he reports leg weakness. Based on this situation, the nurse would correctly suspect what type of imbalance?
Correct Answer: A
Rationale: The patient's symptoms of irregular pulse and leg weakness, along with high ileostomy output, suggest hypokalemia. High ileostomy output can lead to excessive loss of potassium, a key electrolyte responsible for muscle and nerve function. Hypokalemia can cause muscle weakness and cardiac arrhythmias, which align with the patient's symptoms. Hyperkalemia (B) would typically cause muscle cramps and cardiac abnormalities like peaked T-waves, not weakness. Hyponatremia (C) and hypercalcemia (D) do not typically present with these specific symptoms.
Question 5 of 5
What is an expected outcome for Lithium
Correct Answer: D
Rationale: Lithium is commonly used in the treatment of bipolar disorder. One of the expected outcomes of lithium treatment is a decreased incidence of acute manic episodes. Lithium helps stabilize mood and reduce the frequency and severity of manic episodes in patients with bipolar disorder. It is considered one of the first-line treatments for managing symptoms of mania in bipolar disorder. While lithium has various physiological effects in the body, its primary use in mental health is to manage mood symptoms associated with bipolar disorder, particularly the manic phase. Therefore, the expected outcome of lithium treatment is a decrease in the incidence of acute manic episodes.