ATI RN
ATI Capstone Pharmacology Assessment 2 Quizlet Questions
Question 1 of 5
A 48-year-old woman with 2-year history of rheumatoid arthritis has not had sufficient relief with methotrexate alone. Her physician prescribes a biologic TNF-α inhibitor that consists of a recombinant human IgG fused to TNF-α receptor. Which of the following drugs is this?
Correct Answer: C
Rationale: Rheumatoid arthritis (R
A) progression despite methotrexate warrants a TNF-α inhibitor. The description-recombinant human IgG fused to TNF-α receptor-points to Etanercept . Adalimumab and Golimumab are monoclonal antibodies against TNF-α, not receptor fusions. Certolizumab is a PEGylated Fab fragment, not IgG-based. Etanercept , a fusion protein, binds TNF-α, neutralizing it, and matches the question's structure. Infliximab (E) is a chimeric antibody. Etanercept's unique receptor-IgG design distinguishes it, effectively reducing RA inflammation by sequestering TNF-α, a key cytokine, making it the precise answer here.
Question 2 of 5
For which serious adverse effect should the nurse closely monitor a patient who is taking lincosamides?
Correct Answer: D
Rationale: Lincosamides, such as clindamycin, are associated with a high risk of Clostridium difficile-associated diarrhea (CDA
D), a potentially life-threatening condition. CDAD occurs due to the disruption of normal gut flora, allowing C. difficile to overgrow and produce toxins. Symptoms include severe diarrhea, abdominal pain, and fever. While lincosamides can rarely cause hepatotoxicity or ototoxicity, CDAD is the most common and serious adverse effect. Seizures are not typically associated with lincosamides. Early identification and treatment of CDAD are crucial to prevent complications like toxic megacolon or sepsis.
Question 3 of 5
A 5-year-old African American patient has been admitted to the pediatric intensive care unit with pheochromocytoma. The physician has ordered phentolamine. The nurse knows that the other indication for phentolamine is what?
Correct Answer: B
Rationale: Phentolamine (Regitine) is used for the prevention of cell death and tissue sloughing after extravasation of intravenous norepinephrine or dopamine, and severe hypertension reactions caused by manipulation of the pheochromocytoma before and during surgery; diagnosis of pheochromocytoma. Phentolamine would not be indicated for treatment of migraine headaches, life-threatening arrhythmias, or heart failure. The nurse should understand the indications for phentolamine to ensure safe and effective administration.
Question 4 of 5
A 74-year-old professional golfer has chest pain that occurs toward the end of his golfing games. He says the pain usually goes away after one or two sublingual nitroglycerin tablets and rest. What type of angina is he experiencing?
Correct Answer: D
Rationale: The 74-year-old professional golfer is likely experiencing Prinzmetal™s angina, also known as variant angina. This type of angina is characterized by episodes of chest pain that occur at rest or during minimal physical exertion. It is caused by a spasm in the coronary arteries, leading to a temporary reduction or cessation of blood flow to the heart muscle. The chest pain associated with Prinzmetal™s angina can be severe and is often relieved by sublingual nitroglycerin, as described by the golfer. Additionally, the fact that the pain occurs towards the end of his golfing games suggests that it may be triggered by stress or exertion, common triggers for coronary artery spasm in Prinzmetal's angina.
Question 5 of 5
The physician has prescribed haloperidol (Haldol) for the patient with schizophrenia. What is the priority patient outcome?
Correct Answer: B
Rationale: Haloperidol, a conventional antipsychotic, treats schizophrenia by reducing positive symptoms like hallucinations, but its efficacy depends on adherence. The priority outcome is medication compliance, as relapse is common without consistent use, undermining all other goals. Adequate fluids and fiber mitigate side effects (e.g., constipation) but are secondary to ensuring treatment continuity. Decreased hallucinations is a desired effect, not an outcome ensuring it happens. Restlessness indicates side effects (e.g., akathisia), not a goal. Compliance is foundational, as schizophrenia's chronic nature requires long-term management, making choice B the nurse's primary focus for successful therapy.