ATI RN
ATI Intro to Pharmacology Quizlet Questions
Question 1 of 5
A history of which of the following is a contraindication to short-term HRT to prevent menopausal vasomotor symptoms and menopausal vaginitis?
Correct Answer: B
Rationale: Short-term HRT (estrogen ± progestin) relieves menopausal symptoms. Depression isn't a contraindication; HRT may improve mood. Breast cancer is a absolute contraindication due to estrogen's proliferative risk, outweighing benefits. Hysterectomy allows estrogen-only HRT, bronchitis and eczema are unrelated. Breast cancer's link to estrogen drives this restriction, critical for safe hormone use.
Question 2 of 5
Biperiden hydrochloride (Akineton) is added to a list of antiparkinsonian medications that an elderly client is taking. Which of the following instructions made by the nurse that needs further learning?
Correct Answer: C
Rationale: Walking in the morning for direct sunlight is unrelated to the use of biperiden hydrochloride (Akineton) and does not address its side effects or therapeutic effects. Avoiding alcohol and caffeine, managing dry mouth, and increasing fiber and fluid intake are appropriate instructions.
Therefore, the statement about sunlight indicates a need for further learning.
Question 3 of 5
The nurse is preparing to transfuse a patient with a unit of packed red blood cells (PRBCs). Which patient would be best treated with this transfusion?
Correct Answer: B
Rationale: Packed red blood cells (PRBCs) are typically transfused to patients with severe anemia, where the oxygen-carrying capacity of the blood is significantly reduced. PRBCs are concentrated units of red blood cells that can quickly increase the blood's oxygen-carrying capacity. Patients with severe anemia may experience symptoms such as fatigue, weakness, shortness of breath, and pale skin. Transfusion of PRBCs helps to improve oxygen delivery to tissues and organs, alleviating these symptoms and improving the patient's overall well-being.
Question 4 of 5
Action of anticholinergic drugs:
Correct Answer: A
Rationale: Atropine sulfate is an anticholinergic drug that antagonizes the action of acetylcholine at muscarinic receptors. By blocking the parasympathetic nervous system, atropine produces various effects including decreased salivation, increased heart rate, bronchodilation, and mydriasis (pupillary dilation). These properties make atropine useful in treating conditions such as bradycardia, poisoning with certain toxins, and for dilation of the pupil during eye exams.
Question 5 of 5
A 42-year-old woman with a 1-year history of rheumatoid arthritis comes to see her primary care physician complaining of worsening symptoms. She has been taking leflunomide. IL-1 and TNF-α are two key cytokines involved in the negative sequelae of rheumatoid arthritis. Which of the following drugs is a recombinant form of an endogenous IL-1 antagonist?
Correct Answer: B
Rationale: RA involves IL-1 and TNF-α driving inflammation. The question seeks a recombinant IL-1 antagonist. Abatacept inhibits T-cell costimulation, not IL-1. Anakinra , a recombinant IL-1 receptor antagonist (IL-1Ra), blocks IL-1 signaling, matching the description. Methotrexate slows cell proliferation, not an IL-1 antagonist. Hydroxychloroquine modulates immunity differently. Rituximab (E) targets B cells. Anakinra mimics natural IL-1Ra, reducing joint damage in RA when leflunomide fails, directly countering IL-1's effects, unlike broader or unrelated mechanisms of other options.