ATI RN
Practice ATI B Exam Pharmacology Questions
Question 1 of 9
Which of the following is NOT an ester type of local anesthetics:
Correct Answer: D
Rationale: Cocaine is not an ester type of local anesthetic. While procaine, amethocaine, benzocaine, and etidocaine are all ester type local anesthetics, cocaine belongs to the group of local anesthetics known as ester anesthetics. Even though cocaine has local anesthetic properties, it is specifically classified as a "amide type" local anesthetic, not an ester type. Therefore, the correct choice among the given options is D. Cocaine.
Question 2 of 9
Enrique who is under chemotherapy has the following CBC results: WBC 5000/mm3, RBC platelet 10,000/mm3. Which of the following is he at risk for?
Correct Answer: B
Rationale: A platelet count of 10,000/mm3 is critically low and places Enrique at significant risk for bleeding. Platelets are essential for blood clotting, and levels below 20,000/mm3 can lead to spontaneous bleeding, such as nosebleeds, gum bleeding, or internal hemorrhage. While a WBC count of 5000/mm3 is within the normal range, reducing the risk of infection, the extremely low platelet count is the primary concern. Angina is unrelated to platelet counts. Therefore, bleeding is the most immediate risk for Enrique.
Question 3 of 9
A patient is hypokalemic and will be receiving IV potassium. The patient is not on a heart monitor. How should the nurse administer the potassium replacement?
Correct Answer: C
Rationale: When administering IV potassium to a hypokalemic patient who is not on a heart monitor, it's important to ensure a controlled rate of infusion to prevent dangerous cardiac arrhythmias. The recommended maximum rate for IV potassium replacement in this scenario is typically no more than 20 mEq/hour. Faster administration rates can increase the risk of hyperkalemia and potentially lead to serious cardiac complications. Monitoring the patient closely for signs of hyperkalemia such as ECG changes or muscle weakness is also crucial during potassium replacement therapy.
Question 4 of 9
A 6-year-old boy is brought to his primary care physician with a history of hay fever and asthma. He usually has two to three attacks per week. For symptom control, he uses an albuterol inhaler, but his parents would like to try something more. They would like him to take something that would lessen the amount of attacks he has. Although corticosteroids would probably work best for prophylaxis, they are contraindicated in children. He is instead given montelukast. How does montelukast work?
Correct Answer: A
Rationale: Montelukast prevents asthma attacks by blocking leukotriene receptors . Leukotrienes drive inflammation; montelukast reduces this, complementing albuterol's acute relief. Muscarinic blockade is ipratropium's action. COX inhibition (C, D) is NSAIDs'. Lipoxygenase inhibition (E) is zileuton's. Montelukast's specificity suits prophylaxis in this child.
Question 5 of 9
Hormonal agents are used to treat some cancers. An example would be:
Correct Answer: D
Rationale: Estrogen antagonists, such as drugs like Tamoxifen or Fulvestrant, are commonly used to treat hormone receptor-positive breast cancer. These cancer cells have receptors that can bind to estrogen, stimulating their growth. By using estrogen antagonists, the estrogen receptors on the cancer cells are blocked, inhibiting their growth and reducing the risk of cancer recurrence. This makes estrogen antagonists an effective hormonal agent for treating breast cancer.
Question 6 of 9
The nurse is creating a plan of care for a patient with a new diagnosis of hypertension. Which is a potential nursing diagnosis for the patient taking antihypertensive medications?
Correct Answer: B
Rationale: Sexual dysfunction is a potential nursing diagnosis for a patient taking antihypertensive medications. Many antihypertensive medications, especially certain classes like beta-blockers and diuretics, may cause adverse effects such as sexual dysfunction. These medications can impact a patient's libido, sexual arousal, and ability to achieve or maintain an erection, leading to sexual problems. Therefore, sexual dysfunction is an important consideration when caring for a patient with hypertension who is prescribed antihypertensive medications. It is crucial for the nurse to assess, monitor, and address any sexual dysfunction issues that may arise in the patient's care plan to optimize their overall well-being and quality of life.
Question 7 of 9
Regarding phenytoin, all the following are true EXCEPT:
Correct Answer: B
Rationale: Phenytoin's oral bioavailability varies due to formulation and absorption, a true statement. It's highly plasma protein-bound (~90%), not poorly, making that false and the exception. Hepatic enzyme inducers (e.g., rifampicin) enhance its metabolism, true. At higher doses, its elimination shifts to zero-order due to saturated metabolism, true. Half-life ranges from 12-36 hours, also true. High protein binding affects free drug levels, critical for therapeutic monitoring, especially in hypoalbuminemia.
Question 8 of 9
A 4-year-old boy is brought to the emergency department who was found drinking antifreeze while the father was working on their car. A primary component of antifreeze is ethylene glycol, an alcohol converted to toxic metabolites by the liver enzyme alcohol dehydrogenase. To prevent toxicity, the physician could administer ethanol, which would compete with ethylene glycol for the enzyme. In order to avoid administering ethanol to this patient, the physician could instead give which of the following drugs that would also prevent metabolism of ethylene glycol?
Correct Answer: C
Rationale: Ethylene glycol toxicity requires blocking alcohol dehydrogenase. Fomepizole inhibits this enzyme, preventing toxic metabolite formation. Bicarbonate treats acidosis, not metabolism. Disulfiram blocks aldehyde dehydrogenase. Furosemide and Methanol (E) are irrelevant. Fomepizole's specificity avoids ethanol's risks in a child, ensuring safe detoxification.
Question 9 of 9
In the case of an intramuscular injection of a drug:
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.