ATI RN
ATI RN Pharmacology 2023 Questions
Question 1 of 5
The following drugs may be administered transcutaneously to produce their systemic therapeutic effect:
Correct Answer: A
Rationale: GTN patches deliver the drug transdermally, bypassing first-pass metabolism and providing systemic therapeutic action.
Question 2 of 5
Haloperidol:
Correct Answer: B
Rationale: Haloperidol, a typical antipsychotic, causes hypotension less than phenothiazines, so that's not its hallmark. It's highly prone to extrapyramidal side effects (EPS) like dystonia due to strong D2 receptor blockade, a true statement. Arrhythmias (e.g., QT prolongation) occur but aren't its primary issue. Antimuscarinic effects are minimal compared to other antipsychotics. Confusion is possible but not its defining toxicity. EPS prominence drives the need for adjunctive anticholinergics in treatment, a key consideration in schizophrenia management.
Question 3 of 5
A 38-year-old man with hypertension experiences a first ever attack of acute pain, redness and tenderness in the left first metatarsophalangeal joint ('podagra'). His medication is furosemide, calcium carbonate and irbesartan. Serum uric acid is 0.78 mmol/L (upper limit of normal for men 0.48 mmol/L). Which of the following is most appropriate pharmacotherapy?
Correct Answer: D
Rationale: Acute gout (podagra) requires rapid inflammation relief. Paracetamol offers analgesia but no anti-inflammatory effect, inadequate here. Aspirin, at low doses, retains uric acid, worsening gout; at high doses, it's uricosuric but not ideal acutely. Probenecid lowers uric acid long-term, not for acute attacks. Allopurinol prevents gout but can precipitate attacks if started now. Diclofenac, an NSAID, reduces inflammation and pain fast, the most appropriate acute treatment. Its efficacy targets gout's pathophysiology, critical for symptom control.
Question 4 of 5
The nurse routinely includes health teaching about vitamins to patients. Vitamin D has a major role in which process?
Correct Answer: B
Rationale: Vitamin D regulates calcium and phosphorus metabolism, promoting bone health by enhancing intestinal absorption of these minerals. Night blindness (A) is associated with vitamin A deficiency. Growth and development (C) are influenced by multiple vitamins, not just vitamin D. DNA and prothrombin synthesis (D) are unrelated to vitamin D.
Question 5 of 5
The following drugs may be administered transcutaneously to produce their systemic therapeutic effect:
Correct Answer: A
Rationale: GTN patches deliver the drug transdermally, bypassing first-pass metabolism and providing systemic therapeutic action.