ATI RN
ATI Proctored Pharmacology 2023 Quizlet Questions
Question 1 of 5
Drugs which antagonizes the anticoagulant effects of heparin
Correct Answer: C
Rationale: Protamine sulfate is a medication that can antagonize the anticoagulant effects of heparin. Heparin works by binding to antithrombin III to enhance its activity, which leads to the inhibition of factor Xa and thrombin. Protamine sulfate, a positively charged molecule, binds to heparin to form a stable complex, neutralizing the anticoagulant effects of heparin. This makes protamine sulfate a useful antidote for heparin overdose or in situations where rapid reversal of heparin is necessary to reduce the risk of bleeding complications. The other options listed - acetylcysteine, naloxone, warfarin sodium, and phenindione - do not have a direct antagonistic effect on the anticoagulant effects of heparin.
Question 2 of 5
A 25-year-old male comes to the emergency department with crushing, substernal chest pain. The pain radiates up to his jaw and down to his right arm. He has never had chest pain like this before. An ECG shows ST elevations in leads I, II, and AVF. A detailed history reveals that he had used cocaine 2 h prior to the onset of chest pain. Which of the following medications is contraindicated in the treatment of myocardial infarction caused by his cocaine use?
Correct Answer: C
Rationale: Cocaine-induced MI (ST elevations) contraindicates β-blockers . They exacerbate coronary vasospasm via unopposed α-stimulation. ACE inhibitors , aspirin , calcium channel blockers , and nitroglycerin (E) are safe. β-Blockers worsen this unique MI etiology.
Question 3 of 5
The following drugs are contraindicated in asthma:
Correct Answer: B
Rationale: Propranolol, a nonselective beta-blocker, can exacerbate asthma symptoms by causing bronchoconstriction.
Question 4 of 5
A patient about to receive a morning dose of digoxin has an apical pulse of 53 beats/min. What will the nurse do next?
Correct Answer: D
Rationale: The correct action is to check the radial pulse for 1 full minute. When administering digoxin, it is important to assess the apical pulse before giving the medication. A heart rate of 53 beats/min is below the normal range, especially for a patient taking digoxin, which can slow heart rate further. The nurse should check the radial pulse for a full minute to verify the heart rate accurately and assess for any abnormalities. This step is crucial to ensure patient safety and prevent potential complications associated with bradycardia. In this situation, it is necessary to withhold the dose and notify the prescriber to determine the appropriate course of action based on the assessment findings.
Question 5 of 5
A 22-year-old man with seasonal allergic rhinitis takes an antihistamine for relief of symptoms. It is successful for him over 90% of the time. Histamine is a natural amine formed by the decarboxylation of which of the following amino acids?
Correct Answer: C
Rationale: Histamine, key in allergies, is derived from histidine via decarboxylation. L-arginine , Lysine , and Tyrosine (E) form other amines. Heparin is a glycosaminoglycan. Histidine's conversion drives allergic responses, blocked by antihistamines.