ATI RN
Test Bank Pharmacology Questions
Question 1 of 5
Drugs which antagonizes the anticoagulant effects of heparin
Correct Answer: C
Rationale: Protamine sulfate is a medication that can antagonize the anticoagulant effects of heparin. Heparin works by binding to antithrombin III to enhance its activity, which leads to the inhibition of factor Xa and thrombin. Protamine sulfate, a positively charged molecule, binds to heparin to form a stable complex, neutralizing the anticoagulant effects of heparin. This makes protamine sulfate a useful antidote for heparin overdose or in situations where rapid reversal of heparin is necessary to reduce the risk of bleeding complications. The other options listed - acetylcysteine, naloxone, warfarin sodium, and phenindione - do not have a direct antagonistic effect on the anticoagulant effects of heparin.
Question 2 of 5
The nurse teaches a patient taking amphotericin B to report which signs and symptoms to the health care provider?
Correct Answer: C
Rationale: Amphotericin B is an antifungal medication that can cause nephrotoxicity, leading to decreased urine output and renal impairment. Patients should be instructed to report any changes in urinary output promptly. Changes in sight and hearing are not typical adverse effects of amphotericin B. A painful red rash and blisters may indicate an allergic reaction but are less common than nephrotoxicity.
Question 3 of 5
The labor and delivery nurse assists with the delivery of a newborn to a woman taking an adrenergic blocker for a congenital heart defect. What organ systems may be affected in the newborn by these drugs? (Select all that apply.)
Correct Answer: B
Rationale: Adrenergic blockers can affect labor, and babies born to mothers taking these drugs may exhibit adverse cardiovascular, respiratory, and CNS effects. Problems with the GI and GU systems have not been reported. The nurse should monitor the newborn for potential adverse effects and intervene as needed to ensure safety.
Question 4 of 5
A child is receiving methylphenidate. The mother tells the nurse the patient is having trouble sleeping while on the medication. What is the best response by the nurse?
Correct Answer: A
Rationale: Methylphenidate, a stimulant used to treat ADHD, can cause insomnia if taken too late in the day. Administering the medication earlier in the day (before 4:00 pm) can help minimize sleep disturbances. Giving it at 8:00 pm (B) would worsen insomnia. Stopping the medication abruptly (C) is not recommended without consulting the healthcare provider. Diphenhydramine (D) is not a solution for stimulant-induced insomnia.
Question 5 of 5
The client is about to start the treatment for juvenile rheumatoid arthritis. Before the administration of etanercept (Enbrel), it is important for the nurse to:
Correct Answer: A
Rationale: Etanercept is administered via injection, and some formulations may contain latex in the packaging or delivery system. Assessing for a latex allergy is crucial to prevent allergic reactions. While vaccinations and travel plans are important considerations, they are not as critical as ensuring the client's safety regarding potential allergens. Avoiding people who recently received etanercept is not a standard precaution.