Zafirlucast prevents aspirin-sensitive asthma. This consideration is:

Correct Answer: A

Rationale: Step-by-step rationale: 1. Zafirlukast is a leukotriene receptor antagonist used to treat asthma. 2. Aspirin-sensitive asthma is a condition triggered by aspirin and other NSAIDs. 3. Studies have shown that zafirlukast can prevent bronchoconstriction in aspirin-sensitive asthma. 4. Therefore, the statement that Zafirlukast prevents aspirin-sensitive asthma is TRUE. Summary: - Choice A is correct because zafirlukast has been proven to prevent aspirin-sensitive asthma. - Choice B is incorrect as evidence supports the effectiveness of zafirlukast. - Choice C is incorrect as not all choices are true. - Choice D is incorrect as the correct answer is A, making this choice incorrect.

Correct Answer: B

Rationale: The correct answer is B: Propranolol. Class II antiarrhythmics are beta-blockers, which work by blocking the effects of adrenaline on the heart. Propranolol specifically is a non-selective beta-blocker that reduces heart rate and blood pressure, making it effective in treating certain types of arrhythmias. Flecainide (A) is a Class IC antiarrhythmic, Lidocaine (C) is a Class IB antiarrhythmic, and Verapamil (D) is a Class IV antiarrhythmic. These drugs have different mechanisms of action and are not classified as Class II antiarrhythmics.

Correct Answer: B

Rationale: The correct answer is B: Propranolol. Propranolol is a nonselective beta-blocker, meaning it blocks both beta-1 and beta-2 adrenergic receptors. This leads to effects such as decreased heart rate, reduced blood pressure, and bronchoconstriction. Atenolol (choice A) and Metoprolol (choice C) are selective beta-1 blockers, primarily affecting the heart. Nebivolol (choice D) is a beta-1 blocker with vasodilatory properties. By blocking both beta-1 and beta-2 receptors, Propranolol has a wider range of effects compared to the other choices.

Correct Answer: A

Rationale: The correct answer is A: TRUE. Ergot and indol derivatives, along with NSAIDs, are indeed main agents for acute migraine attack treatment. Ergot derivatives like ergotamine and dihydroergotamine are vasoconstrictors that help alleviate migraine symptoms by reducing blood flow in the brain. Indol derivatives like sumatriptan are serotonin receptor agonists that also help relieve migraines. NSAIDs like ibuprofen can help reduce inflammation and pain associated with migraines. Therefore, the statement is true. Summary of other choices: B: FALSE - This choice is incorrect as the statement in the question is true. C: Null - This choice is incorrect as it does not provide any relevant information to the question. D: All - This choice is incorrect as it implies that all agents are main agents for acute migraine attack treatment, which is not accurate.

Correct Answer: D

Rationale: Step 1: Sulphonylureas are a class of drugs that stimulate insulin release. Step 2: They act by binding to the sulphonylurea receptor on beta islet cells of the pancreas. Step 3: This binding triggers a cascade of events leading to insulin release. Step 4: Insulin then helps lower blood glucose levels. Conclusion: Choice D is correct as it accurately describes the mechanism of action of sulphonylureas. Choices A, B, and C are incorrect as they do not reflect the primary mode of action of sulphonylureas.