Wilms' tumor (nephroblastoma), an embryonal malignancy of the kidney, is the most common renal tumor of childhood. The tumor suppressor WTI is associated with familial Wilms Tumor and its locus is IlpDNA was extracted from the normal tissue and tumor of a patient with Wilms' tumor, and from the blood of the patient's father and mother. Electrophoresis (southern blot) was performed for a polymorphic marker (A) which is close to WTI. Based on the figure, which of the following is the most likely to explain the mutation in this patient's cancer?

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