ATI RN
microbiology chapter 13 test bank Questions
Question 1 of 9
While studying the pneumonic infection in 1928 the English doctor Frederick Griffith discovered:
Correct Answer: B
Rationale: The correct answer is B: Transformation. Frederick Griffith discovered bacterial transformation, where genetic material can be transferred between bacteria. He observed this phenomenon while studying pneumonia-causing bacteria in 1928. Transformation is the process by which bacteria take up external DNA and incorporate it into their own genome. This discovery was crucial in understanding how genetic information can be transferred between organisms. Rationale for other choices: A: Translation - This term refers to the process of protein synthesis from mRNA, not relevant to Griffith's discovery. C: Transcription - This term refers to the process of synthesizing RNA from DNA, not related to Griffith's discovery. D: Conjugation - This term refers to the direct transfer of genetic material between bacterial cells through cell-to-cell contact, which is different from the phenomenon Griffith observed.
Question 2 of 9
Young man is hospitalized in pulmonology with complaints of dry cough, fatigue and suffocations. The anamnesis and the lab tests lead to pneumocystis pneumonia. The CD4+ cells are less than 200/mm3. What test you will order:
Correct Answer: B
Rationale: The correct answer is B: For HIV. Pneumocystis pneumonia in a young man with CD4+ cells less than 200/mm3 is highly suggestive of HIV infection. HIV weakens the immune system, leading to opportunistic infections like pneumocystis pneumonia. Testing for HIV is crucial for diagnosis and appropriate management. Explanation for other choices: A: Testing for ureaplasma urealyticum is not indicated in this case as the symptoms and CD4+ cell count point towards an HIV-related infection. C: Testing for Treponema pallidum (syphilis) is not relevant in the context of a young man with pneumocystis pneumonia and low CD4+ cell count. D: Testing for Neisseria gonorrhoea is not appropriate in this scenario as the symptoms and CD4+ cell count suggest an underlying HIV infection rather than a bacterial sexually transmitted infection.
Question 3 of 9
Which structure protects bacteria from phagocytosis?
Correct Answer: B
Rationale: The correct answer is B: Capsule. Capsules are a protective layer outside the bacterial cell wall that helps bacteria evade phagocytosis by immune cells. The capsule inhibits phagocytic cells from engulfing the bacteria, making it difficult for them to be recognized and destroyed. A: Flagella - Flagella are not involved in protecting bacteria from phagocytosis. They are responsible for bacterial movement. C: Endospore - Endospores are dormant, resistant structures formed by some bacteria in response to harsh conditions. They do not directly protect against phagocytosis. D: Pili - Pili are hair-like structures used for adhesion and conjugation, not for protection against phagocytosis.
Question 4 of 9
A wound culture from a patient with an infected ulcer revealed Gram-positive rods with terminal spores. What is the most likely causative agent?
Correct Answer: A
Rationale: Step-by-step rationale: 1. Gram-positive rods with terminal spores suggest Clostridium genus. 2. Terminal spores are characteristic of Clostridium perfringens. 3. C. perfringens is known to cause wound infections. 4. Therefore, the most likely causative agent is Clostridium perfringens. Summary: A: Clostridium perfringens is correct due to its characteristic features and association with wound infections. B: Bacillus anthracis does not typically form terminal spores. C: Clostridium tetani causes tetanus, not wound infections. D: Bacillus cereus does not produce terminal spores like Clostridium perfringens.
Question 5 of 9
Langerhans cells, which play a role in defense against microbes, are located in the:
Correct Answer: A
Rationale: The correct answer is A: epidermis. Langerhans cells are a type of immune cell found in the epidermis, the outermost layer of the skin. They play a crucial role in the defense against microbes by capturing and presenting antigens to activate the immune system. The dermis (B), hypodermis (C), and subcutaneous layer (D) are located deeper in the skin and do not contain Langerhans cells. Therefore, the epidermis is the correct location for these immune cells to carry out their defensive functions.
Question 6 of 9
For cultivation of Brucella, pure cultures should be incubated in CO2 enriched atmosphere. What type of breathing is typical for Brucella?
Correct Answer: A
Rationale: The correct answer is A: Capnophilic. Brucella requires a CO2 enriched atmosphere for cultivation, making it capnophilic. This is because Brucella is a microaerophilic bacterium that thrives in low oxygen conditions and elevated CO2 levels. Choice B (Facultative anaerobic) and D (Obligate aerobic) are incorrect as Brucella does not grow well under aerobic conditions. Choice C (Obligate anaerobic) is also incorrect as Brucella can grow in the presence of oxygen, although it prefers low oxygen environments.
Question 7 of 9
Which description matches most to adenoviruses:
Correct Answer: A
Rationale: Step-by-step rationale: 1. Adenoviruses are DNA viruses, so choices B and C (ssRNA and DNA) are incorrect. 2. Adenoviruses have a middle-sized, naked icosahedral capsid, making choice A the correct description. 3. Choice D is incorrect as adenoviruses do have specific characteristics, making "None of the above" an inaccurate option. In summary, the correct answer A is supported by the fact that adenoviruses have a middle-sized, naked icosahedral capsid and contain double-stranded DNA. Choices B, C, and D are incorrect as they do not align with the characteristics of adenoviruses.
Question 8 of 9
A male patient has been diagnosed with gastric ulcer. Bacteriological examination of biopsy material from the affected part of stomach revealed small colonies of gram-negative, oxide reductase-positive flexibacteria that grew on the chocolate agar on the fifth day. Which of the following microorganisms is the most likely causative agent?
Correct Answer: A
Rationale: The correct answer is A: Helicobacter pylori. This bacterium is the most likely causative agent of gastric ulcers. Here's the rationale: 1. Helicobacter pylori is commonly associated with gastric ulcers. 2. It is a gram-negative bacterium that grows on chocolate agar and is oxide reductase-positive. 3. The slow growth on the fifth day is characteristic of H. pylori. 4. Campylobacter jejuni and Campylobacter fetus are not typically associated with gastric ulcers. 5. Mycoplasma hominis is a bacterium that lacks a cell wall and is not commonly found in gastric ulcers.
Question 9 of 9
While studying the pneumonic infection in 1928 the English doctor Frederick Griffith discovered:
Correct Answer: B
Rationale: The correct answer is B: Transformation. Frederick Griffith discovered bacterial transformation, where genetic material can be transferred between bacteria. He observed this phenomenon while studying pneumonia-causing bacteria in 1928. Transformation is the process by which bacteria take up external DNA and incorporate it into their own genome. This discovery was crucial in understanding how genetic information can be transferred between organisms. Rationale for other choices: A: Translation - This term refers to the process of protein synthesis from mRNA, not relevant to Griffith's discovery. C: Transcription - This term refers to the process of synthesizing RNA from DNA, not related to Griffith's discovery. D: Conjugation - This term refers to the direct transfer of genetic material between bacterial cells through cell-to-cell contact, which is different from the phenomenon Griffith observed.