ATI RN
Immune System Medication Questions
Question 1 of 5
While studying for a pharmacology test, a student asks his peers about interferons. What statement about interferons is accurate?
Correct Answer: D
Rationale: Interferons are proteins released by cells in response to viral infections. Choice D is correct because interferons interfere with viral replication within infected cells by activating antiviral proteins. Choices A, B, and C are incorrect because interferons do not stimulate B-lymphocyte activity, interfere with stem cell multiplication, or stimulate growth and differentiation of lymphocytes. Interferons primarily function as part of the innate immune response to combat viral infections.
Question 2 of 5
The nursing class is studying monoclonal antibodies. What monoclonal antibody reacts to human T cells, disabling them and acting as an immune suppressor?
Correct Answer: D
Rationale: The correct answer is D, Muromonab-CD3. This monoclonal antibody specifically targets and reacts with human T cells, disabling them and acting as an immune suppressor. Muromonab-CD3 is used in conditions where T cells need to be suppressed, such as in transplant rejection. A: Adalimumab targets tumor necrosis factor-alpha, not T cells. B: Cetuximab targets epidermal growth factor receptor, not T cells. C: Rituximab targets CD20 antigen on B cells, not T cells.
Question 3 of 5
The nurse is caring for a patient with an allograft transplant. The physician orders a monoclonal antibody to prevent rejection of the transplant. What monoclonal antibody would the nurse expect to be ordered?
Correct Answer: B
Rationale: The correct answer is B: Daclizumab. Daclizumab is a monoclonal antibody that targets IL-2 receptors on T cells, preventing their activation and proliferation, thus reducing the risk of transplant rejection. Alemtuzumab (A) targets CD52 on T and B cells for leukemia treatment. Erlotinib (C) is a tyrosine kinase inhibitor for cancer. Omalizumab (D) targets IgE for allergic asthma.
Question 4 of 5
The nurse is caring for a female patient, aged 62, who has been admitted for treatment of metastatic melanoma. What agent would the nurse anticipate the physician is likely to order?
Correct Answer: D
Rationale: The correct answer is D: Ipilimumab. This drug is a checkpoint inhibitor used in the treatment of metastatic melanoma by enhancing the immune system to fight cancer cells. It is a common choice for this condition due to its effectiveness. Aldesleukin (A) and Interferon alfa 2b (B) are also immunotherapy agents but are not typically used as first-line treatments for metastatic melanoma. Cyclosporine (C) is an immunosuppressant used to prevent organ transplant rejection and manage autoimmune diseases, not for treating melanoma.
Question 5 of 5
What interleukin receptor antagonist would the nurse anticipate is most likely to be ordered for a patient, 25 years old, who has not responded to traditional antirheumatic drugs?
Correct Answer: B
Rationale: The correct answer is B: Anakinra (Kineret). Anakinra is an interleukin-1 receptor antagonist, which is used to treat patients with rheumatoid arthritis who have not responded to traditional antirheumatic drugs. Interleukin-1 is a key cytokine involved in the inflammatory response seen in rheumatoid arthritis. By blocking the action of interleukin-1, Anakinra helps reduce inflammation and joint damage in these patients. A: Natalizumab (Tysabri) is a monoclonal antibody used to treat multiple sclerosis by preventing immune cells from crossing the blood-brain barrier. C: Eculizumab (Soliris) is a monoclonal antibody used to treat rare blood disorders by blocking a specific part of the immune system. D: Adalimumab (Humira) is a tumor necrosis factor (TNF) inhibitor used to treat various autoimmune diseases like rheumatoid arthritis, ps