ATI RN
Microbiology An Evolving Science Test Bank Questions
Question 1 of 9
While examining a blood smear taken form a patient and stained by Romanovsky's method a doctor revealed some protozoa and diagnozed the patient with Chagas disease. What protozoan is the causative agent of this disease?
Correct Answer: A
Rationale: Rationale: 1. Chagas disease is caused by Trypanosoma cruzi. 2. Trypanosoma cruzi is transmitted by triatomine bugs. 3. On a blood smear stained with Romanovsky's method, Trypanosoma cruzi appears as trypomastigotes. 4. Toxoplasma gondii causes toxoplasmosis, not Chagas disease. 5. Leishmania donovani and Leishmania tropica cause different forms of leishmaniasis, not Chagas disease.
Question 2 of 9
Anti-influenza drugs that target the neuraminidase are;
Correct Answer: D
Rationale: The correct answer is D: Relenza and Tamiflu. Both Relenza and Tamiflu are anti-influenza drugs that target the neuraminidase enzyme of the influenza virus, thereby inhibiting its replication and spread. Maxi Grip (A) is not an anti-influenza drug, Theraflu (B) contains different active ingredients, and Amantadine and Rimantadine (C) target a different viral protein, M2 ion channel. Therefore, choices A, B, and C are incorrect as they do not specifically target neuraminidase for influenza treatment.
Question 3 of 9
A wound culture revealed Gram-positive cocci in clusters. The bacteria were catalase-positive and coagulase-negative. What is the most likely microorganism?
Correct Answer: A
Rationale: The correct answer is A: Staphylococcus epidermidis. The presence of Gram-positive cocci in clusters indicates a staphylococcal species. The fact that the bacteria are catalase-positive and coagulase-negative further narrow it down to Staphylococcus epidermidis, as this species fits all the given characteristics. - Choice B, Staphylococcus aureus, is coagulase-positive. - Choice C, Streptococcus pyogenes, is a streptococcal species, not staphylococcal. - Choice D, Enterococcus faecalis, is a Gram-positive cocci but is catalase-negative and not typically found in clusters.
Question 4 of 9
Which of the following statements for genus Klebsiella is correct?
Correct Answer: A
Rationale: The correct answer is A because Klebsiella species have a real capsule, which is a distinguishing feature used for their identification. This capsule helps them evade the host immune response. Additionally, Klebsiella species are non-motile, meaning they do not possess flagella for movement. Choices B and C are incorrect because Klebsiella species are facultative anaerobes and do not form spores under any conditions. Choice D is also incorrect as option A is the correct statement for genus Klebsiella.
Question 5 of 9
Quite often, the soil may contain a number of pathogenic microorganisms. The causative agents of the following disease may exist in the soil for a long time:
Correct Answer: A
Rationale: The correct answer is A: Anthrax. Anthrax is caused by the bacterium Bacillus anthracis, which can form spores that are highly resistant and can survive in the soil for long periods. These spores can remain dormant until they come into contact with a susceptible host, leading to infection. Diphtheria, viral hepatitis, and pertussis are caused by different types of pathogens (bacteria and viruses) that do not have the same ability to persist in soil as anthrax spores. Therefore, the causative agents of these diseases are less likely to exist in the soil for extended periods compared to anthrax spores.
Question 6 of 9
The process of bacterial conjugation involves:
Correct Answer: C
Rationale: The correct answer is C: Direct transfer of DNA between two bacterial cells. In bacterial conjugation, genetic material is transferred directly from one bacterial cell to another through a conjugative pilus. This process involves physical contact between the cells, followed by the transfer of plasmid DNA or chromosomal DNA. This mechanism allows for the exchange of genetic information between bacteria, leading to genetic diversity. Explanation of why other choices are incorrect: A: DNA transfer via bacteriophage - Bacteriophage is a virus that infects bacteria and transfers its genetic material, but this is not the mechanism involved in bacterial conjugation. B: Uptake of naked DNA from the environment - This process is known as transformation, where bacteria take up free DNA from the environment, but it is not specific to bacterial conjugation. D: Binary fission - Binary fission is a form of asexual reproduction in bacteria where a single cell divides into two identical cells, and it is not related to the process
Question 7 of 9
The cell envelope in gram positive bacteria is:
Correct Answer: A
Rationale: The correct answer is A: Two-layer. In gram-positive bacteria, the cell envelope consists of two layers: the thick peptidoglycan layer and the cytoplasmic membrane. The peptidoglycan layer is much thicker compared to gram-negative bacteria, providing structural support and protection. The cytoplasmic membrane is located beneath the peptidoglycan layer and serves as a barrier between the cytoplasm and the external environment. The other choices are incorrect because gram-positive bacteria do have a cell envelope, it is composed of two layers, not three layers, and it is not just a single layer. Choice D is incorrect as it states that there is no cell envelope in gram-positive bacteria, which is not true.
Question 8 of 9
Which of the following antibodies is synthesized by the infant soon after birth?
Correct Answer: B
Rationale: The correct answer is B: IgM. IgM is the first antibody synthesized by the infant soon after birth. It is produced by B cells in response to initial exposure to antigens. IgA is mainly found in mucosal areas, IgG is transferred from mother to fetus, and IgD functions in the early stages of B cell development. Therefore, IgM is the most suitable choice as the antibody synthesized by the infant soon after birth.
Question 9 of 9
A bacteriophage is a(n) ____________ virus.
Correct Answer: D
Rationale: The correct answer is D: complex. Bacteriophages are considered complex viruses because they have a complex structure consisting of a polyhedral head, a helical tail, and tail fibers. The head contains the viral genetic material, while the tail facilitates attachment to the host bacterial cell. This complexity distinguishes bacteriophages from simpler viruses like helical and icosahedral viruses. Helical viruses have a rod-like shape, while icosahedral viruses have a symmetrical, 20-sided structure. Enveloped viruses have a lipid bilayer envelope surrounding their capsid, which bacteriophages lack. Therefore, the unique and intricate structure of bacteriophages classifies them as complex viruses.