Which vitamin is recommended for all women of childbearing age to reduce the risk of neural tube defects such as spina bifida?

Correct Answer: D

Rationale: Folic acid is the correct answer. All women of childbearing age are recommended to take folic acid to reduce the risk of neural tube defects such as spina bifida in their offspring. Neural tube defects occur in the early stages of pregnancy, often before a woman even knows she is pregnant, which is why it is important for all women of childbearing age to ensure they have adequate folic acid intake. Folic acid is a B vitamin that helps the body make new cells and plays a crucial role in the development of the baby's neural tube, which eventually becomes the brain and spinal cord. Adequate folic acid intake before and during pregnancy can significantly reduce the risk of neural tube defects. That's why it is recommended for all women of childbearing age to take a daily folic acid supplement or consume foods fortified with folic acid.

Correct Answer: D

Rationale: Nephrosis, also known as nephrotic syndrome, is characterized by the presence of massive proteinuria (excretion of more than 3.5 grams of protein in the urine per day), hypoalbuminemia (low levels of albumin in the blood), and edema (swelling due to fluid retention). These are the hallmark clinical manifestations of nephrosis. Proteinuria results from damage to the glomerular filtration barrier, leading to the loss of proteins, particularly albumin, in the urine. Hypoalbuminemia occurs due to the excessive loss of albumin in the urine, leading to reduced oncotic pressure in the bloodstream. Edema develops as a result of decreased oncotic pressure, which causes fluid to leak from the blood vessels into the tissues, especially in the lower extremities and around the eyes. Other common manifestations of nephrosis may include hyperlipidemia, lipid

Correct Answer: C

Rationale: Methotrexate is a chemotherapy medication that is commonly used in the treatment of various types of cancers, including leukemia. Leukemia is a cancer of the blood and bone marrow that affects the white blood cells. Methotrexate works by interfering with the growth and division of cancer cells, thereby helping to slow down or stop the progression of the disease. It is not typically used to treat thalassemia, hemophilia, or sickle cell anemia, as these conditions are not cancers and require different types of treatment approaches.

Correct Answer: D

Rationale: Brown adipose tissue (BAT) is specialized adipose tissue found in newborns and hibernating mammals, whose primary function is to generate heat through non-shivering thermogenesis. This heat generation is essential for maintaining body temperature in newborns, especially as they have a larger surface area-to-volume ratio, which results in greater heat loss compared to adults. BAT produces heat by metabolizing stored lipids and disrupting the normal process of cellular respiration, leading to the production of heat instead of ATP. The heat generated by BAT is then distributed throughout the body to help maintain a stable core body temperature in newborns, who are not yet able to regulate their body temperature as effectively as adults.

Correct Answer: D

Rationale: Granulocytic sarcoma is most commonly associated with acute myeloid leukemia (AML).