ATI RN
microbiology a systems approach test bank Questions
Question 1 of 9
Which type of bacteria is responsible for causing tuberculosis?
Correct Answer: B
Rationale: The correct answer is B: Mycobacterium tuberculosis. Mycobacterium tuberculosis is the bacteria responsible for causing tuberculosis. This bacterium has unique cell wall components that make it resistant to the body's immune defenses, allowing it to survive and multiply within the host. Streptococcus pyogenes (Choice A), Escherichia coli (Choice C), and Bacillus anthracis (Choice D) are not associated with tuberculosis. Streptococcus pyogenes is known for causing strep throat and skin infections, Escherichia coli is commonly involved in gastrointestinal infections, and Bacillus anthracis causes anthrax.
Question 2 of 9
A patient in the oral surgery department has got purulent complication. Bacteriological analysis of the wound material found a culture that produces cyan pigment. What microorganism is the most probable causative agent?
Correct Answer: A
Rationale: The correct answer is A: Pseudomonas aeruginosa. Pseudomonas aeruginosa is known for producing a bluish-green pigment called pyocyanin, which presents as a cyan pigment. This bacterium is commonly associated with wound infections and is often found in oral surgery complications. Proteus vulgaris (B) and Klebsiella pneumoniae (D) are not typically associated with cyan pigment production, making them less likely causative agents. Bacillus subtilis (C) is not known to produce cyan pigment and is not a common pathogen in wound infections. Therefore, based on the presence of cyan pigment and the clinical context of an oral surgery complication, Pseudomonas aeruginosa is the most probable causative agent.
Question 3 of 9
After starting treatment for pulmonary tuberculosis a patient complained about red tears and urine. What drug could cause such changes?
Correct Answer: A
Rationale: The correct answer is A: Rifampicin. Rifampicin is known to cause red discoloration of bodily fluids, including tears and urine, due to its side effect of harmless color changes. Benzylpenicillins (B and C) and Biseptol-480 do not typically cause such discoloration. Rifampicin's mechanism of action involves binding to bacterial RNA polymerase, leading to inhibition of RNA synthesis, which is unrelated to the mechanism of the other drugs. Thus, based on the unique side effect profile of Rifampicin and its mechanism of action, it is the most likely drug causing red tears and urine in this scenario.
Question 4 of 9
The function of beta-lactamase in bacteria is to:
Correct Answer: A
Rationale: The correct answer is A: Break down antibiotics like penicillin. Beta-lactamase is an enzyme produced by bacteria to inactivate beta-lactam antibiotics like penicillin by breaking the beta-lactam ring. This mechanism helps bacteria resist the antibiotic's effects. The other choices are incorrect because beta-lactamase does not enhance protein synthesis, facilitate DNA replication, or transport nutrients. It specifically targets and deactivates beta-lactam antibiotics, making choice A the most appropriate answer.
Question 5 of 9
The specific prevention (by vaccination) of the disease gas gangrene (caused by Clostridium perfringens) is based on:
Correct Answer: B
Rationale: The correct answer is B: Anatoxin. An anatoxin is a toxin that has been rendered harmless while retaining its ability to stimulate an immune response. Gas gangrene is caused by the toxins produced by Clostridium perfringens, not the bacteria itself. Therefore, vaccination with an anatoxin can trigger the immune system to produce antibodies against the toxin, providing immunity against the disease. A: Killed whole cell vaccine - Gas gangrene is caused by toxins, not the whole bacterium. This type of vaccine may not be effective in preventing the disease. C: There is no specific prevention by vaccination - This is incorrect, as vaccination with an anatoxin can prevent gas gangrene. D: Alive attenuated vaccine - Attenuated vaccines contain live, weakened forms of the pathogen. However, for gas gangrene prevention, targeting the specific toxin with an anatoxin vaccine is more appropriate.
Question 6 of 9
Which one is true for enteropathogenic E.coli?
Correct Answer: A
Rationale: The correct answer is A because enteropathogenic E. coli (EPEC) have fimbrial adhesins that help them bind to enterocytes in the intestines, leading to colonization and infection. This is a key virulence factor of EPEC. Explanation for why other choices are incorrect: B: EPEC typically cause watery diarrhea in infants, not bloody diarrhea similar to shigellosis. C: EPEC are not part of the normal intestinal flora; they are pathogenic bacteria. D: EPEC are not invasive and do not typically produce enterotoxin; they primarily adhere to the intestinal epithelium.
Question 7 of 9
Cultural characteristics of bacteria are:
Correct Answer: C
Rationale: The correct answer is C because cultural characteristics of bacteria refer to their growth patterns on different culture media, including liquid and solid agars. Bacteria exhibit unique growth patterns that can be observed and studied on these media. Choice A is incorrect as it refers to isolation techniques, not cultural characteristics. Choice B is incorrect as it describes metabolic activities, not cultural characteristics. Choice D is incorrect as it dismisses the essential aspect of bacterial growth on culture media.
Question 8 of 9
Which of the following bacteria is associated with Lyme disease?
Correct Answer: A
Rationale: The correct answer is A: Borrelia burgdorferi. This bacterium is associated with Lyme disease, a tick-borne illness. Borrelia burgdorferi is transmitted to humans through the bite of infected black-legged ticks. It causes a range of symptoms, including fever, rash, joint pain, and neurological problems. Summary: B: Clostridium botulinum is associated with botulism, a serious illness caused by a toxin produced by this bacterium. C: Escherichia coli is a common bacterium found in the intestines of humans and animals, some strains can cause food poisoning. D: Streptococcus pneumoniae is a bacterium that can cause pneumonia and other respiratory infections, but not Lyme disease.
Question 9 of 9
A sputum smear stained by Gram's method revealed Gram-positive cocci in clusters. The patient presented with an abscess. What is the causative agent?
Correct Answer: A
Rationale: The correct answer is A: Staphylococcus aureus. Staphylococcus aureus is a Gram-positive bacterium that commonly presents as cocci in clusters. It is a known causative agent of abscesses due to its ability to produce enzymes and toxins that contribute to tissue destruction. In this case, the presence of Gram-positive cocci in clusters aligns with the characteristic morphology of Staphylococcus aureus. Summary of incorrect choices: B: Streptococcus pyogenes is a Gram-positive bacterium that typically presents as cocci in chains, not clusters. It is more commonly associated with pharyngitis and skin infections rather than abscesses. C: Enterococcus faecalis is a Gram-positive bacterium that typically presents as cocci in pairs or short chains, not clusters. It is more commonly associated with urinary tract infections and endocarditis. D: Micrococcus luteus is a Gram-positive bacterium that typically presents as t