ATI RN
Hematology Final Exam Questions Pdf Questions
Question 1 of 5
Which test provides a definitive diagnosis of aplastic anemia?
Correct Answer: B
Rationale: A bone marrow aspiration is the definitive test used to diagnose aplastic anemia by evaluating marrow cellularity.
Question 2 of 5
The first laboratory marker in progressive iron deficiency anemia is
Correct Answer: B
Rationale: Falling serum ferritin (B) is the earliest marker of iron deficiency, reflecting depleted stores before marrow hemosiderin (A), serum iron/TIBC changes (C), or anemia (D, E) develop.
Question 3 of 5
The best diagnostic test for paroxysmal nocturnal hemoglobinuria (PNH) is
Correct Answer: D
Rationale: Flow cytometry (D) detecting GPI-anchored protein loss (e.g., CD55, CD59) is the gold standard for PNH, more specific than HAM (A), sucrose lysis (B), complement (C), or marrow study (E).
Question 4 of 5
The criteria for successful bone marrow transplantation in thalassemic patients include all the following EXCEPT
Correct Answer: C
Rationale: Successful BMT in thalassemia favors young age (A), no hepatomegaly (B), no iron overload (D), and HLA match (E). Bone deformities (C) don’t preclude success, though they indicate disease severity.
Question 5 of 5
Hereditary intrinsic factor deficiency (HIFD), formerly called congenital pernicious anemia, differs from the typical adult pernicious anemia by all the following EXCEPT
Correct Answer: D
Rationale: HIFD presents early (A), with normal acid (B), histology (C), and no antibodies (D), unlike adult PA. Lack of endocrine disorders (E) is true for both, as HIFD isn’t autoimmune.