ATI RN
Safety Pharmacology Across the Lifespan Questions
Question 1 of 5
Which term describes when two drugs compete for the same receptor site, resulting in increased activity of the first drug?
Correct Answer: D
Rationale: The correct answer is D: Displacement. When two drugs compete for the same receptor site, one drug can displace the other, leading to increased activity of the first drug. This phenomenon is known as drug displacement. A: Desired action does not describe the competition between drugs for the same receptor site. B: Synergistic effect refers to when two drugs work together to produce a greater effect than the sum of their individual effects. C: Carcinogenicity relates to the ability of a substance to cause cancer, and is not relevant to the scenario described in the question.
Question 2 of 5
Which of the following drugs would be appropriate for this patient?
Correct Answer: D
Rationale: The correct answer is D: Voriconazole. This drug is appropriate for the patient as it is a broad-spectrum antifungal agent commonly used to treat invasive fungal infections. It is effective against a wide range of fungal species, including Candida and Aspergillus. Voriconazole has good tissue penetration and high bioavailability, making it suitable for serious systemic fungal infections. Flucytosine (A) is mainly used in combination with other antifungal agents and is not a standalone therapy. Terbinafine (B) is primarily used for dermatophyte infections and not for systemic fungal infections. Griseofulvin (C) is used for superficial fungal infections like ringworm and is not effective against systemic fungal infections like those requiring Voriconazole.
Question 3 of 5
Which of the following medications is commonly prescribed for the prevention of blood clots in patients after surgery?
Correct Answer: B
Rationale: The correct answer is B: Enoxaparin. Enoxaparin is a low molecular weight heparin commonly prescribed for post-surgery blood clot prevention due to its effectiveness in inhibiting blood clot formation. Warfarin (A) is primarily used for long-term anticoagulation therapy, not typically for post-surgery prevention. Aspirin (C) is a mild antiplatelet agent and is not as effective as enoxaparin for post-surgery clot prevention. Clopidogrel (D) is also an antiplatelet drug but is not commonly prescribed for post-surgery blood clot prevention.
Question 4 of 5
A 50-year-old female with diabetes is prescribed liraglutide. Liraglutide works by:
Correct Answer: A
Rationale: The correct answer is A: Increasing insulin secretion and inhibiting glucagon release. Liraglutide is a GLP-1 receptor agonist that stimulates insulin secretion from pancreatic beta cells and inhibits glucagon secretion. This leads to improved blood glucose control in patients with diabetes. Choice B is incorrect because liraglutide does not primarily work by improving insulin sensitivity in peripheral tissues. Choice C is incorrect because liraglutide does not inhibit the absorption of glucose in the intestines. Choice D is incorrect because liraglutide does not inhibit the enzyme that breaks down incretin hormones.
Question 5 of 5
Which of the following drugs is used to treat or prevent bacterial infections by inhibiting bacterial cell wall synthesis?
Correct Answer: A
Rationale: The correct answer is A: Penicillin. Penicillin is a beta-lactam antibiotic that works by inhibiting bacterial cell wall synthesis, leading to bacterial cell death. This mechanism makes penicillin effective against a wide range of bacterial infections. Azithromycin (B) and Ciprofloxacin (C) are antibiotics that work by inhibiting bacterial protein synthesis and DNA replication, respectively, not cell wall synthesis. Amoxicillin (D) is also a beta-lactam antibiotic like penicillin, but it is not the best choice here as penicillin is more commonly used for cell wall synthesis inhibition.