ATI RN
Pharmacology ATI Test Bank Questions
Question 1 of 5
Which statement regarding the use of zolpidem (Ambien) for insomnia is accurate?
Correct Answer: B
Rationale: Zolpidem's absorption slows with food (e.g., high-fat meals), delaying sleep onset, per pharmacokinetics. Tyramine isn't relevant-no MAOI link. It's Category C (pregnancy risk), not safe in breastfeeding. It's a non-benzo hypnotic. Food delay is accurate, affecting use.
Question 2 of 5
A 58-year-old woman who is obese comes to the emergency department with diaphoresis and crushing chest pain that radiates to her left arm. The physician orders an ECG and checks her cardiac enzymes to confirm his suspicion of myocardial infarction. Because of the quick response and intervention, she survives and is ultimately discharged with a prescription for low-dose daily aspirin to inhibit platelet aggregation. Which of the following enzymes is the intended target of aspirin in this patient?
Correct Answer: A
Rationale: Aspirin post-MI inhibits platelet aggregation via cyclooxygenase (COX) . It blocks thromboxane A2 synthesis, reducing clotting. Lipoxygenase , phospholipase A2 , prostacyclin synthase , and thromboxane synthase (E) aren't primary targets. COX inhibition prevents secondary events.
Question 3 of 5
Which drug is most likely to be ordered for the client with herpes simplex virus?
Correct Answer: A
Rationale: Herpes simplex virus requires antiviral therapy, and acyclovir inhibits viral DNA replication, reducing symptom duration and severity, making it the standard treatment. Zidovudine targets HIV, not HSV. Nystatin is antifungal, ineffective against viruses. Metronidazole treats bacterial/protozoal infections. Acyclovir's specificity for HSV, backed by clinical guidelines, ensures targeted therapy, making A the most likely drug ordered for effective management.
Question 4 of 5
An older adult patient will be taking a vasodilator for hypertension. Which adverse effect is of most concern for the older adult patient taking this class of drug?
Correct Answer: D
Rationale: The most concerning adverse effect for an older adult patient taking a vasodilator for hypertension is hypotension, which refers to abnormally low blood pressure levels. Older adults are more susceptible to experiencing drops in blood pressure due to age-related changes in their cardiovascular system. Vasodilators work by dilating blood vessels, which can further lower blood pressure. Excessive hypotension can lead to symptoms such as dizziness, lightheadedness, weakness, and falls, which can be particularly dangerous for older adults who are at a higher risk of injury. Close monitoring of blood pressure and gradual dosage titration are essential in older adult patients to minimize the risk of hypotension.
Question 5 of 5
When should a patient taking omeprazole be administered the medication?
Correct Answer: C
Rationale: Omeprazole is a proton pump inhibitor commonly used to treat conditions such as acid reflux and ulcers. It is typically recommended to be taken in the morning on an empty stomach, at least 30 minutes before the first meal of the day. This is because omeprazole works best when the stomach is empty to ensure optimal absorption and effectiveness of the medication. Taking omeprazole with food or at other times of the day may reduce its potency and could lead to suboptimal results in managing the patient's condition.