ATI RN
Common Pediatric Genetic Disorders Questions
Question 1 of 5
Which statement is true?
Correct Answer: C
Rationale: Most cancers are sporadic, resulting from multiple somatic mutations over time.
Question 2 of 5
cells are commonly used today in research laboratories. They are from a cervical cancer patient who died in 1951:
Correct Answer: A
Rationale: HeLa cells, from Henrietta Lacks’ cervical cancer, are widely used in research.
Question 3 of 5
The characteristic indicated by the blackened figures is probably:
Correct Answer: A
Rationale: Without the pedigree, dominant is assumed if blackened figures appear in every generation; recessive if skipping generations.
Question 4 of 5
Consanguinity shows a strong association with which pattern of inheritance?
Correct Answer: B
Rationale: Consanguinity increases the risk of autosomal recessive disorders due to shared rare alleles.
Question 5 of 5
Large triplet repeat expansions can be detected by:
Correct Answer: C
Rationale: Southern blotting is used for large repeat expansions (e.g., Huntington’s), as PCR may fail with very large repeats.