Which scientist is most responsible for ending the controversy about spontaneous generation?

Correct Answer: C

Rationale: The correct answer is C: Louis Pasteur. He conducted experiments that definitively disproved the theory of spontaneous generation through his famous swan-neck flask experiment. By showing that microorganisms only appeared in the broth when exposed to air, Pasteur demonstrated that they did not arise spontaneously. John Needham's experiments were inconclusive, Joseph Lister is known for his contributions to antiseptic surgery, and Robert Koch is credited with developing Koch's postulates for identifying the causative agents of diseases, but neither of them directly contributed to ending the controversy about spontaneous generation.

Correct Answer: A

Rationale: The correct answer is A: Type 1 hypersensitivity reaction. In this type of reaction, allergens trigger the production of IgE antibodies, leading to mast cell and basophil degranulation and release of inflammatory mediators like histamine. This causes immediate allergic symptoms. Seafood and eggs are common allergens that can elicit this response. B: Type 2 hypersensitivity reaction involves antibodies targeting cell surface or extracellular matrix antigens, leading to cell destruction or dysfunction. This is not the mechanism in seafood or egg allergies. C: Type 3 hypersensitivity reaction involves immune complex deposition in tissues, leading to inflammation and tissue damage. This is not the mechanism in seafood or egg allergies. D: Type 4 hypersensitivity reaction is cell-mediated and involves T cells causing inflammation and tissue damage. This is not the mechanism in seafood or egg allergies.

Correct Answer: A

Rationale: The correct answer is A: Neutralization. In this experiment, the ABE botulinum antitoxin serum is introduced along with the extract to neutralize the botulinum toxin. This is a specific type of serological reaction where the antitoxin serum binds to and neutralizes the toxin, preventing it from causing harm. Summary: - B: Precipitation involves the formation of visible insoluble complexes, which is not the case in this experiment. - C: Complement binding involves the activation of complement proteins, which is not the main mechanism at play here. - D: Double immunodiffusion is a technique to detect the presence of specific antigens or antibodies, but it is not directly related to the neutralization of toxins as seen in this experiment.

Correct Answer: B

Rationale: The correct answer is B because a viral capsid is a protein coat that surrounds and protects the viral nucleic acid (DNA or RNA). It helps in the attachment of the virus to host cells and protects the genetic material during transmission. Choice A is incorrect because a viral capsid is composed of proteins, not an envelope. Choice C is incorrect because not all viruses have an outer membrane. Choice D is incorrect because a viral capsid is primarily made up of proteins, not lipids.

Correct Answer: A

Rationale: The correct answer is A: Leptospira. The key features pointing to Leptospira are the presence of convoluted bacteria resembling C and S letters, which is characteristic of Leptospira species. Leptospirosis presents with fever, jaundice, haemorrhagic rash, and acute renal insufficiency. The other choices (B: Treponema, C: Spirilla, D: Borrelia) do not match the histological description or the clinical presentation of the case. Treponema is associated with syphilis, Spirilla with genus Spirochaeta, and Borrelia with Lyme disease, none of which match the given scenario.

Correct Answer: A

Rationale: The correct answer is A because Staphylococcus aureus can develop resistance to penicillin over time due to the production of beta-lactamase enzymes. This resistance mechanism makes it no longer susceptible to penicillin. The other choices are correct: B) S. aureus can produce beta hemolysis, C) it produces various toxins like hemolysins, leucocidins, and enterotoxins, and D) it shows a positive catalase reaction due to the presence of catalase enzyme that converts hydrogen peroxide to water and oxygen.

Correct Answer: A

Rationale: Correct Answer: A Rationale: 1. Enteropathogenic E. coli (EPEC) attach to enterocytes via a type III secretion system. 2. Once attached, they form attaching and effacing lesions on the microvilli, leading to microvillus destruction. 3. This mechanism allows EPEC to cause diarrhea by disrupting the normal absorptive function of the intestines. Summary: - B (They are invasive and produce enterotoxin) is incorrect because EPEC are non-invasive and do not produce enterotoxins. - C (Cause disease clinically similar to bacterial) is vague and does not provide specific information about EPEC pathogenesis. - D (None of the above) is incorrect as A is the correct explanation for EPEC pathogenicity.

Correct Answer: B

Rationale: The correct answer is B: dermis. The papillary layer is located in the dermis, specifically at the junction with the epidermis. It contains capillaries, lymphatics, and sensory receptors, contributing to the skin's strength and elasticity. The epidermis (choice A) is the outermost layer of the skin, while the hypodermis (choice C) and subcutaneous layer (choice D) are deeper layers beneath the dermis, primarily composed of fat cells and connective tissue. Therefore, the papillary layer is part of the dermis, making choice B the correct answer.

Correct Answer: A

Rationale: The correct answer is A: Nucleoid. The bacterial genome is located in the nucleoid, a region within the bacterial cell where the genetic material is condensed and organized. This structure is not the same as a nucleus found in eukaryotic cells. The other choices (B: Nucleotide and C: ATP) are incorrect because nucleotide refers to a building block of DNA or RNA, and ATP is a molecule used for energy transfer in cells, neither of which specifically houses the bacterial genome. Choice D: None of the above is incorrect as well, as the correct term for the compact structure containing the bacterial genome is the nucleoid.