ATI RN
Quizlet Pharmacology ATI Questions
Question 1 of 5
Which organ is the most responsible for the first-pass effect?
Correct Answer: C
Rationale: The liver, via portal vein metabolism, drives the first-pass effect, reducing oral drug bioavailability (e.g., morphine) before systemic circulation. Bladder and kidneys excrete, not metabolize first. Stomach degrades some, but liver's enzyme activity dominates. First-pass is liver-centric, shaping dosing.
Question 2 of 5
What is an adverse reaction to Montelukast? (select all that apply)
Correct Answer: B
Rationale: A. Stroke is not typically associated with an adverse reaction to Montelukast. The most common adverse reactions include neuropsychiatric events such as mood changes, suicidal thoughts/behaviors, and allergic reactions affecting the skin and mucous membranes.
Question 3 of 5
Which condition does the nurse identify as a late manifestation of hypokalemia?
Correct Answer: C
Rationale: Palpitations are a late manifestation of hypokalemia. Hypokalemia is a condition characterized by low levels of potassium in the blood, which can affect the heart's ability to function properly. Palpitations, or irregular heartbeat, can occur as a result of the heart's increased sensitivity to adrenaline due to low potassium levels. Other early manifestations of hypokalemia include muscle weakness, which is a result of potassium's role in muscle contraction, hypotension (low blood pressure), and lethargy.
Question 4 of 5
While a patient is receiving antilipemic therapy, the nurse knows to monitor the patient closely for the development of which problem?
Correct Answer: D
Rationale: Antilipemic therapy is used to lower cholesterol levels in the blood. This type of therapy often places a strain on the liver as it metabolizes and processes the cholesterol-lowering medications. Therefore, patients receiving antilipemic therapy are at an increased risk of developing liver dysfunction. The nurse should monitor the patient closely for signs and symptoms of liver dysfunction, such as jaundice, abdominal pain, nausea, vomiting, and changes in liver function tests. Early detection and intervention can help prevent serious complications associated with liver dysfunction.
Question 5 of 5
A female patient needs a whole blood transfusion. In order for transfusion services (the blood bank) to prepare the correct product a sample of the patient's blood must be obtained for:
Correct Answer: B
Rationale: A blood type and crossmatch are essential before a whole blood transfusion to ensure compatibility between the donor and recipient. This process involves determining the patient's blood type (ABO and Rh) and testing for antibodies that could cause a transfusion reaction. A complete blood count and differential are not required for transfusion preparation. Blood culture and sensitivity are used to diagnose infections, not for transfusion compatibility. Therefore, blood type and crossmatch are the correct steps.