Which one of the following statements about the mechanisms of action of antiviral drugs is least accurate?

Nurselytic

Home

ATI RN

ATI RN

ATI RN Test Bank

ABVD chemotherapy drugs Questions

Question 1 of 5

Which one of the following statements about the mechanisms of action of antiviral drugs is least accurate?

A. The initial step in activation of famciclovir in HSV-infected cells is its phosphorylation by viral thymidine kinase B. The reverse transcriptase of HIV is 30-50 times more sensitive to inhibition by indinavir than host cell DNA polymerases C. Gancicolvir inhibits viral DNA polymerase but does not cause chain termination D. Increased activity of host cell phosphodiesterases that degrade tRNA is one of the antiviral actions of interferons

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

Which statement regarding phase-specific chemotherapic agents is correct? They

A. Are most effective in one phase of the cell cycle B. Effective in all phases of the cell cycle C. Are only effective in G0 phase D. Include the alkylating agents

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Methenamine salts are used as urinary antiseptics. The reason why they lack systemic antibacterial action is that they are

A. Not absorbed into the systemic circulation following oral ingestion B. Rapidly metabolized by liver drug-metabolizing enzymes C. Converted to formaldehyde only at low urinary pH D. Substrates for active tubular secretion

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

Certain anaerobic protozoan parasites lack mitochondria and generate energy-rich compounds, such as acetyl-CoA, by means of enzymes present in organelles called hydrogenosomes. An important enzyme involved in this process is

A. Cytochrome P450 B. Glycerol - 3 - phosphate oxidase C. Hypoxanthine-guanine phosphoribosyltransferase D. Pyruvate - ferredoxin oxidoreductase

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

Which of the following drugs enhances GABA actions on the neuromuscular junctions of nematodes and arthropods?

A. Glutamic acid B. Ivermectin C. Picrotoxin D. Pyrantel pamoate

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Access More Questions!

ATI RN Basic

$89/ 30 days

ATI RN Premium

$150/ 90 days

Similar Questions