ATI RN
Pediatric Immunization NCLEX Questions Questions
Question 1 of 5
Which one of the following sets of cells can present antigen to helper T cells?
Correct Answer: A
Rationale: B cells and dendritic cells are professional antigen-presenting cells (APCs) that express MHC class II and present antigens to helper T cells.
Question 2 of 5
Matching: Immunodeficiency - Lymphopenia plus severe neutropenia
Correct Answer: C
Rationale: Reticular dysgenesis is a severe condition with both lymphopenia and neutropenia due to failure of lymphoid and myeloid precursors.
Question 3 of 5
Which of the following is not a prominent feature of Wiskott-Aldrich syndrome?
Correct Answer: D
Rationale: Wiskott-Aldrich syndrome (WAS) features eczema, thrombocytopenia, and infections, but leukopenia is not typical; lymphocyte counts may be normal or reduced, not a prominent feature.
Question 4 of 5
A 6-month-old presents with recurrent cellulitis and bacteremias due to Staphylococcus aureus. The white blood cell count is 2500 with 5% neutrophils, 10% eosinophils, 35% monocytes, and 50% lymphocytes. The platelet count is 650,000. A brother and a female cousin died at the age of 18 months and 2 years, respectively. The most likely diagnosis is
Correct Answer: C
Rationale: Kostmann disease (severe congenital neutropenia) fits with persistent neutropenia, recurrent Staphylococcus aureus infections, and a family history suggesting autosomal recessive inheritance.
Question 5 of 5
A 15-month-old male child presented with thrombocytopenic purpura, atopic dermatitis, and recurrent infections caused by cytomegalovirus and P.jiroveci. Immunoglobulin assay revealed elevated IgE and IgA with decreased IgM levels. Of the following, the MOST likely diagnosis is
Correct Answer: A
Rationale: Wiskott-Aldrich syndrome is characterized by eczema, thrombocytopenia, and recurrent infections with abnormal immunoglobulin levels (elevated IgE/IgA, low IgM).