Which one of the following is characteristic of both phenytoin and carbamazepine?

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Pharmacology Practice Exam ATI Questions

Question 1 of 5

Which one of the following is characteristic of both phenytoin and carbamazepine?

Correct Answer: D

Rationale: Phenytoin and carbamazepine are antiepileptic drugs with a shared mechanism: they stabilize neuronal membranes by preventing sodium influx through fast sodium channels, reducing excitability and controlling seizures, particularly in partial and tonic-clonic types. Both induce hepatic cytochrome P450 enzymes, accelerating metabolism of other drugs, not inhibiting it. Phenytoin exhibits zero-order elimination at high doses due to enzyme saturation, while carbamazepine follows first-order kinetics, so this isn't a shared trait. They reduce the efficacy of oral contraceptives by inducing their metabolism, not enhancing them. Safety in pregnancy is questionable, with both linked to teratogenicity (e.g., fetal hydantoin syndrome). The sodium channel blockade is the fundamental property uniting their therapeutic effects, making it the key characteristic they share, critical to their role in epilepsy management.

Question 2 of 5

The patient has been prescribed dextromethorphan (Delsym). What medication information should the nurse provide?

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

A client is prescribed an intranasal corticosteroid. What should the nurse include in client education about this drug?

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

The nurse administers IV furosemide (Lasix) to a client with heart failure. Which finding indicates a therapeutic effect?

Correct Answer: A

Rationale: Furosemide reduces fluid overload in heart failure by diuresis, decreasing edema , a direct therapeutic sign. BP may drop, not rise. Heart rate isn't primary'preload reduction matters. Thirst is a side effect. Edema reduction aligns with furosemide's action, critical in heart failure where congestion drives symptoms, making A the key finding.

Question 5 of 5

The following drugs may be administered transcutaneously to produce their systemic therapeutic effect:

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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