Which one of the following cytokines plays the most important role in protection against intracellular growth (reactivation) of Mycobacterium tuberculosis?

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Pediatric Immunizations NCLEX Questions Questions

Question 1 of 5

Which one of the following cytokines plays the most important role in protection against intracellular growth (reactivation) of Mycobacterium tuberculosis?

Correct Answer: A

Rationale: IFN-γ activates macrophages to kill intracellular Mycobacterium tuberculosis.

Question 2 of 5

If a virus snuck into the body, which of the following would you expect to be the last killer?

Correct Answer: C

Rationale: Helper T cells act indirectly via cytokines, making them the last to contribute to killing compared to direct cytotoxic mechanisms.

Question 3 of 5

A very high serum concentrations of one or more immunoglobulin classes, suggest all the following EXCEPT

Correct Answer: C

Rationale: Intestinal lymphangiectasia causes protein loss, including immunoglobulins, leading to low, not high, levels. The others can elevate immunoglobulins due to infection or inflammation.

Question 4 of 5

The earliest clinical feature of ataxia-telangiectasia is

Correct Answer: A

Rationale: Ataxia, due to cerebellar degeneration, is typically the earliest sign of ataxia-telangiectasia, appearing in early childhood.

Question 5 of 5

Recurrent infections with neutropenia are a distinctive feature of

Correct Answer: D

Rationale: GSDIb impairs neutrophil function and production due to glucose-6-phosphate transporter defects, leading to recurrent infections.

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