Which one of the following agents increases phagocytosis by macrophages in patients with chronic granulomatous disease?

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Question 1 of 5

Which one of the following agents increases phagocytosis by macrophages in patients with chronic granulomatous disease?

Correct Answer: B

Rationale: Interferon-γ enhances macrophage phagocytosis in chronic granulomatous disease by boosting immune function.

Question 2 of 5

Which of the following is used in active immunization of children and combines bacterial toxoids with a bacterial antigen?

Correct Answer: C

Rationale: DTP (Diphtheria, Tetanus, Pertussis) combines toxoids (diphtheria, tetanus) and a bacterial antigen (pertussis) for active immunization in children.

Question 3 of 5

Which one of the following compounds enhances immune function in vitro and in clinical trials decreases the symptoms of the common cold?

Correct Answer: A

Rationale: Echinacea is known to enhance immune function and has evidence of reducing common cold symptoms in clinical trials.

Question 4 of 5

In the management of patients with AIDS, the sulfonamides are often used in combination with inhibitors of folate reductase. However, such combinations have minimal activity against

Correct Answer: D

Rationale: Trimethoprim-sulfamethoxazole has minimal activity against Treponema pallidum (syphilis), which requires penicillin or other drugs.

Question 5 of 5

A 54-year-old farmer has a 5-year history of frequent, recurrent, and very painful kidney stones. Appropriate chronic therapy for this man is

Correct Answer: B

Rationale: Hydrochlorothiazide reduces calcium excretion in urine, making it appropriate for chronic management of calcium-based kidney stones.

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