ATI RN
openstax microbiology test bank Questions
Question 1 of 9
Which one is NOT included in the etiology of osteomyelitis
Correct Answer: B
Rationale: The correct answer is B: EBV. Osteomyelitis is primarily caused by bacteria, not viruses like Epstein-Barr virus (EBV). The main pathogens involved in osteomyelitis are typically Staphylococcus aureus, including Methicillin-resistant Staphylococcus aureus (MRSA), Haemophilus influenzae, and Pseudomonas aeruginosa. EBV is not a causative agent of osteomyelitis. It is crucial to differentiate between bacterial and viral etiologies in infectious diseases to guide appropriate treatment.
Question 2 of 9
Which one belongs to genus Orthopoxvirus?
Correct Answer: D
Rationale: The correct answer is D because all three viruses, Vaccinia virus, Smallpox virus, and Cowpox virus, belong to the genus Orthopoxvirus. They share similar characteristics and genetic makeup. Vaccinia virus is used as a vaccine against smallpox, Smallpox virus causes smallpox disease, and Cowpox virus can infect both animals and humans. Choice A, B, and C are incorrect because each of these viruses is a member of the Orthopoxvirus genus.
Question 3 of 9
What is the major function of the bacterial capsule?
Correct Answer: B
Rationale: The correct answer is B: Protection against phagocytosis. The bacterial capsule is a protective layer outside the cell wall that helps bacteria evade phagocytosis by the host immune system. It acts as a physical barrier against immune cells like macrophages and neutrophils, allowing the bacteria to survive and multiply in the host. Energy production (A), DNA replication (C), and protein synthesis (D) are essential cellular functions but are not directly associated with the major function of the bacterial capsule, which is protection against phagocytosis.
Question 4 of 9
The lipophilization is:
Correct Answer: A
Rationale: The correct answer is A because lipophilization is the process of removing water from cells under deep vacuum in a frozen state. Dehydration of the cell at a low temperature helps to preserve the cellular structure and components. Choice B is incorrect as hydration does the opposite of what lipophilization aims to achieve. Choice C is incorrect as lipophilization does not involve enriching cells with proteins. Choice D is incorrect as lipophilization does not involve removing protein content from cells.
Question 5 of 9
Which one of the following microbiological diagnostic methods is the most suitable for detection of genitourinary chlamydiosis
Correct Answer: D
Rationale: The correct answer is D: PCR. PCR (Polymerase Chain Reaction) is the most suitable method for detecting genitourinary chlamydiosis due to its high sensitivity and specificity in detecting the genetic material of Chlamydia trachomatis. PCR can detect even low levels of the pathogen, providing accurate results. A: Cultural diagnostic is not as sensitive as PCR and may take longer to produce results. B: ELISA detects antibodies, which may not be present in early stages of infection, leading to false-negative results. C: CFT (Complement Fixation Test) is an older method with lower sensitivity compared to PCR for detecting chlamydiosis.
Question 6 of 9
During fibergastroscopy a patient with ulcer disease of the stomach, the mucosal biopsy is taken from the area of an ulcer. Impression smear is prepared from biopsy material and stained by Gram method; the rest of biopsy material is tested for urease activity. Microscopy of the impression smear revealed gram- negative spiral-shaped microorganisms, urease activity test is positive. What bacteria were detected?
Correct Answer: A
Rationale: The correct answer is A: Helicobacter pylori. Rationale: 1. Gram-negative spiral-shaped microorganisms match the morphology of Helicobacter pylori. 2. Positive urease activity is a characteristic feature of Helicjsonacter pylori. 3. Helicobacter pylori is specifically associated with gastric ulcers and is a common pathogen in the gastrointestinal tract. Summary: Choice B, Campilobacter jejuni, is a gram-negative curved bacterium but is not typically associated with gastric ulcers or urease activity. Choice C, Treponema pallidum, is a spirochete bacterium causing syphilis, which is not related to gastric ulcers. Choice D, Spirilla minor, is a generic term for spiral-shaped bacteria and is not a specific pathogen associated with gastric ulcers or urease activity.
Question 7 of 9
A mercury-containing compound used as a preservative in vaccines is:
Correct Answer: D
Rationale: The correct answer is D: thimerosal. Thimerosal is a mercury-containing compound used as a preservative in vaccines. It helps prevent contamination and growth of bacteria and fungi in multi-dose vials. Choice A, analgesic, refers to pain relievers, not preservatives. Choice B, EDTA, is a chelating agent used to bind metal ions and is not a preservative. Choice C, codeine, is an opioid pain medication and not a preservative used in vaccines. Thimerosal is the correct answer as it specifically fits the description of a mercury-containing compound used in vaccines.
Question 8 of 9
Which one is NOT included in the etiology of osteomyelitis
Correct Answer: B
Rationale: The correct answer is B: EBV. Osteomyelitis is primarily caused by bacteria, not viruses like Epstein-Barr virus (EBV). The main pathogens involved in osteomyelitis are typically Staphylococcus aureus, including Methicillin-resistant Staphylococcus aureus (MRSA), Haemophilus influenzae, and Pseudomonas aeruginosa. EBV is not a causative agent of osteomyelitis. It is crucial to differentiate between bacterial and viral etiologies in infectious diseases to guide appropriate treatment.
Question 9 of 9
DNA transfer from one bacterium to another through phages is termed as:
Correct Answer: B
Rationale: The correct answer is B: Transduction. In bacterial genetics, transduction refers to the process of DNA transfer from one bacterium to another via bacteriophages. During transduction, the bacteriophage infects a bacterium, incorporating bacterial DNA into its own genome, which is then transferred to another bacterium upon infecting it. Rationale: A: Transfection is the process of introducing foreign DNA into eukaryotic cells, not bacteria. C: Induction is the process of activating gene expression in a cell. D: Infection is a general term for the invasion of pathogens into a host organism, not specific to DNA transfer via phages in bacteria.