Which one belongs to genus Orthopoxvirus

Correct Answer: D

Rationale: The correct answer is D, All of these. Orthopoxvirus genus includes Vaccinia, Smallpox, and Cowpox viruses. They share similar characteristics such as brick-shaped virions and double-stranded DNA genomes. Vaccinia virus is used in smallpox vaccine, Smallpox virus caused the eradicated disease, and Cowpox virus can infect both animals and humans. Therefore, all three viruses belong to the Orthopoxvirus genus. Choices A, B, and C are incorrect because they each represent a different virus from the genus Orthopoxvirus.

Correct Answer: C

Rationale: The correct answer is C because Koch's postulate states that a microorganism must be isolated in pure culture, grown in a laboratory setting, and then inoculated into animals to reproduce the same disease seen in the original host. This step demonstrates a direct cause-and-effect relationship between the isolated microorganism and the disease. Choice A is incorrect because not all cases of a disease may have the same microorganism present. Choice B is incorrect as isolating the microorganism alone does not prove its pathogenicity. Choice D is incorrect as it does not address the need for experimental reproduction of the disease in a new host.

Correct Answer: D

Rationale: Step-by-step rationale: 1. Infectious process triggers an immune response to fight off the invading pathogen. 2. The immune response can lead to inflammation, fever, and production of antibodies. 3. Hypersensitivity reactions can also occur in response to the infection. 4. Options A, B, and C are not defining features of the infectious process. Summary: Option D is correct because an infectious process typically leads to an immune response and possibly hypersensitivity reactions. Options A, B, and C are incorrect as they do not specifically relate to the immune response or hypersensitivity reactions in the context of an infectious process.

Correct Answer: A

Rationale: The correct answer is A: Lipopolysaccharides. Endotoxins are a type of bacterial toxin found in the outer membrane of Gram-negative bacteria. They consist of lipid A, which is a lipid component, and polysaccharides, making them lipopolysaccharides. Lipoproteins (choice B) and glycoproteins (choice C) do not accurately describe the chemical structure of endotoxins. "None of the above" (choice D) is incorrect as lipopolysaccharides are indeed the chemical structure of endotoxins.

Correct Answer: C

Rationale: The correct answer is C because the main factor in the pathogenicity of diphtheria is the exotoxin produced by the bacterium Corynebacterium diphtheriae. This exotoxin inhibits protein synthesis in host cells, leading to tissue damage and the characteristic symptoms of diphtheria. A: The metachromatic bodies of Ernst-Babes are not the main factor in diphtheria pathogenicity. B: While endotoxins can contribute to the pathogenicity of some bacteria, in diphtheria, the main factor is the exotoxin. D: This is incorrect as the main factor in diphtheria pathogenicity is the exotoxin.