ATI RN
microbiology an introduction test bank Questions
Question 1 of 9
Which of the statements below IS NOT CORRECT
Correct Answer: B
Rationale: The correct answer is B because live vaccines can potentially revert to a virulent form, although this is extremely rare. This is due to the live attenuated virus in the vaccine potentially mutating back to a more dangerous form. Live vaccines are designed to be weakened but there is a small risk of reversion. Therefore, statement B is not correct. A: This statement is correct as immunocompromised individuals may have adverse reactions to live vaccines due to their weakened immune system. C: This statement is correct as microbes with many serotypes can make it challenging to develop a vaccine that covers all variations. D: This statement is correct as side effects to vaccination, although usually mild and temporary, can occur in some individuals.
Question 2 of 9
According to their optimal growth temperatures, microorganisms are divided into:
Correct Answer: C
Rationale: Rationale: 1. Psychrophilic: Grow best in cold temperatures 2. Mesophilic: Grow best in moderate temperatures 3. Thermophilic: Grow best in high temperatures - Choice A is incorrect as "thermophobic" is not a recognized term. - Choice B is incorrect as "psychophobic" is not a recognized term. - Choice D is incorrect as "mesophobic" is not a recognized term.
Question 3 of 9
The patient has developed pain in the axillary area, rise of temperature developed 10 hours ago. On examination: shaky gait is marked, the tongue is coated by white coating. The pulse is frequent. The painful lymphatic nodules are determined in the axillary area. The skin is erythematous and glistering over the lymphatic nodules. What is the most probable diagnosis?
Correct Answer: D
Rationale: The most probable diagnosis is D: Tularemia. Tularemia is a bacterial infection caused by Francisella tularensis. The symptoms described align with tularemia, such as pain in axillary area, fever, shaky gait, coated tongue, frequent pulse, painful lymphatic nodules, and erythematous skin over nodules. The key features pointing towards tularemia are the presence of lymphadenitis in the axillary area and the erythematous, glistering skin over the nodules, which are characteristic of ulceroglandular tularemia. Bubonic plague (A) presents with painful, swollen lymph nodes called buboes but typically lacks the erythematous skin findings. Acute purulent lymphadenitis (B) usually presents with pus-filled lymph nodes but does not typically cause shaky gait or coated tongue. Lymphogranulomatosis (C) is a term for Hodgkin's lymphoma, which does not
Question 4 of 9
A 19 year old woman suffers from primary syphilis. Doctor administered her complex therapy that includes benzylpenicillin sodium salt. What is the mechanism of action of this drug?
Correct Answer: A
Rationale: The correct answer is A. Benzylpenicillin sodium salt, also known as penicillin G, works by blocking the synthesis of peptidoglycan in the microbial cell wall. Peptidoglycan is crucial for the structural integrity of bacterial cell walls. By inhibiting its synthesis, penicillin disrupts the cell wall formation, leading to cell lysis and bacterial death. Choices B, C, and D are incorrect because penicillin does not target cytoplasm proteins, thiol enzymes, or RNA synthesis. Penicillin's primary mode of action is specifically related to interfering with bacterial cell wall synthesis.
Question 5 of 9
A patient presented with a painful, swollen lymph node, and bacteremia. A Gram-negative rod with a characteristic safety pin appearance was observed. What is the causative agent?
Correct Answer: A
Rationale: Step 1: Gram-negative rod with safety pin appearance indicates bipolar staining. Step 2: Yersinia pestis is a Gram-negative rod causing bubonic plague. Step 3: Y. pestis has bipolar staining due to its unique F1 capsule. Step 4: The swollen lymph node and bacteremia are consistent with bubonic plague. Step 5: Therefore, the correct answer is A: Yersinia pestis. Summary: - B: Clostridium tetani causes tetanus, not characterized by a safety pin appearance. - C: Brucella melitensis causes brucellosis, not characterized by a safety pin appearance. - D: Pasteurella multocida causes animal bites infections, not characterized by a safety pin appearance.
Question 6 of 9
Pili are also called:
Correct Answer: B
Rationale: The correct answer is B: microvilli. Pili are hair-like structures found on the surface of some bacteria, while microvilli are microscopic cellular projections that increase surface area for absorption in cells like intestinal cells. Pili are involved in bacterial adhesion, while microvilli are important for nutrient absorption. Therefore, the correct answer is B. Incorrect choices: A: Fimbriae are short, thin appendages found on the surface of some bacteria, mainly used for adhesion. C: Cilia are hair-like structures found on the surface of some eukaryotic cells, often involved in movement or sensory functions. D: Flagella are long, whip-like appendages used for bacterial motility.
Question 7 of 9
A patient with pneumonia had sputum cultured on Endo agar, revealing red colonies. The bacteria were Gram-negative rods. What is the most likely causative agent?
Correct Answer: A
Rationale: Rationale for correct answer (A: Escherichia coli): 1. Endo agar selects for Gram-negative bacteria. 2. Red colonies on Endo agar indicate lactose fermentation, characteristic of E. coli. 3. E. coli is a common cause of pneumonia, especially in immunocompromised patients. Summary of why other choices are incorrect: - B: Klebsiella pneumoniae: Typically forms mucoid colonies on agar. - C: Pseudomonas aeruginosa: Produces characteristic greenish-blue colonies on agar. - D: Proteus mirabilis: Does not typically ferment lactose, so would not produce red colonies on Endo agar.
Question 8 of 9
Which of the following bacteria produces a neurotoxin that causes botulism?
Correct Answer: A
Rationale: The correct answer is A: Clostridium botulinum. Clostridium botulinum produces the neurotoxin that causes botulism. This bacterium thrives in anaerobic conditions and contaminated food. The neurotoxin blocks acetylcholine release at the neuromuscular junction, leading to muscle paralysis. Choices B, C, and D are incorrect because Clostridium tetani causes tetanus, Escherichia coli can cause food poisoning but not botulism, and Staphylococcus aureus produces enterotoxins causing food poisoning, not botulism.
Question 9 of 9
Which bacteria are responsible for causing bacterial meningitis?
Correct Answer: D
Rationale: The correct answer is D, "All of the above." Bacterial meningitis can be caused by Neisseria meningitidis, Haemophilus influenzae, and Streptococcus pneumoniae. These bacteria are common pathogens associated with meningitis. Each of them can lead to serious infections in the brain and spinal cord. Neisseria meningitidis is known for causing meningococcal meningitis, Haemophilus influenzae is a common cause of H. influenzae meningitis, and Streptococcus pneumoniae is responsible for pneumococcal meningitis. Therefore, since all three bacteria can cause bacterial meningitis, the correct answer is D. Choices A, B, and C are incorrect because each of these bacteria individually can cause bacterial meningitis; it is not limited to just one specific type.