Which of the recently introduced antiepileptics is useful in absence seizure?

Correct Answer: A

Rationale: Newer antiepileptic drugs like ethosuximide and valproate are effective in treating absence seizures which are generalized brief and involve loss of consciousness.

Correct Answer: D

Rationale: The patient self-injected what he believed to be heroin, which is commonly sold on the street. Fentanyl is a potent synthetic opioid that is often mixed with or sold as heroin due to its powerful effects. Therefore, the patient most likely took Fentanyl, as it is frequently associated with street drugs like heroin.

Correct Answer: C

Rationale: Acetylsalicylic acid (aspirin) inhibits COX enzymes, reducing prostaglandin synthesis (choice D), yielding analgesic (choice A) and antipyretic (choice B) effects by decreasing pain mediators and hypothalamic heat regulation, respectively. However, it inhibits, not promotes, platelet aggregation (choice C) by blocking thromboxane A2 production, a pro-aggregatory prostaglandin, making it antiplatelet, used in cardiovascular prophylaxis. Promotion of aggregation would contradict its mechanism. This exception tests understanding of aspirin's unique antiplatelet action among NSAIDs, critical for its clinical applications.

Correct Answer: D

Rationale: Ketamine can increase heart rate and is contraindicated in conditions like sick sinus syndrome.

Correct Answer: D

Rationale: Levothyroxine (choice D) treats hypothyroid goiter (low T3/T4) by replacing thyroid hormone, shrinking the gland. TSH infusion (choice A) worsens it, Propranolol (choice B) manages hyperthyroid symptoms, Propylthiouracil (choice C) reduces hormone in hyperthyroidism. Levothyroxine is appropriate.