Which of the following was most likely the injected dose of cocaine (in mg)?

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Principles of Pharmacology Quizlet Questions

Question 1 of 5

Which of the following was most likely the injected dose of cocaine (in mg)?

Correct Answer: D

Rationale: The injected dose of cocaine can be calculated using the formula Dose = Cp * Vd, where Cp is the plasma concentration, and Vd is the volume of distribution. Given that the plasma level of cocaine was 0.75 mg/L, and the volume of distribution is about 130 L, the injected dose can be calculated as 0.75 * 130 = 97.5 mg, which is closest to option D.

Question 2 of 5

The figure below depicts the in vitro log dose-response curves of different drugs acting on the same receptor. Drug Z was able to antagonize the effects of both drug X and drug Y. Which of the following terms best defines drug X?

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

What percentage of atenolol would be bound if a dose of 50 mg/d was administered to the patient?

Correct Answer: B

Rationale: The correct answer is B (5%) because the question is asking for the bound percentage of atenolol after a specific dose has been administered. Since the dose is 50 mg/d, the correct answer can be calculated as 50 mg/d / 1000 mg/g x 0.10 (10%) = 5%. This calculation shows that 5% of the atenolol would be bound.

Question 4 of 5

Which of the following was the most likely cause of the patient's disorder?

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

Which of the following terms best defines this drug interaction?

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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