Which of the following viruses does not belong to family Paramyxoviridae:

Correct Answer: D

Rationale: The correct answer is D: Rubella virus. Rubella virus does not belong to the family Paramyxoviridae because it belongs to the Togaviridae family. The other choices, A (Measles virus), B (Respiratory syncytial virus), and C (Mumps virus) are all members of the Paramyxoviridae family. This classification is based on the genetic and structural characteristics of the viruses. Rubella virus is distinct in its genetic composition and replication cycle compared to the Paramyxoviridae family, making it the correct choice.

Correct Answer: D

Rationale: Rationale: 1. Rickettsiae are obligate intracellular bacteria, hence they do not form spores, capsules, or flagella. 2. They have a slim glycocalyx layer, aiding in attachment to host cells. 3. Bipolar fimbriae are structures that help in adhesion to host cells. Therefore, all statements (A, B, and C) are true for Rickettsiae, making option D the correct answer. Other choices are incorrect as they do not accurately describe the characteristics of Rickettsiae.

Correct Answer: C

Rationale: The correct answer is C because Leptospira cannot be cultivated on blood and chocolate agar. The bacterium requires specialized media such as Ellinghausen-McCullough-Johnson-Harris (EMJH) medium for growth. Blood and chocolate agar do not provide the necessary nutrients for the bacterium's growth. Leptospira is a fastidious organism that has unique culture requirements. Therefore, the statement that Leptospira can be cultivated on blood and chocolate agar is incorrect. The other choices are correct: A - Leptospirosis is an acute infectious disease with a typical geographic distribution, B - Reservoirs of leptospira are different wild and domestic animals, mainly rodents, and D - Doxycycline and penicillins are drugs of choice for the treatment of leptospirosis.

Correct Answer: B

Rationale: The correct answer is B: Reverse transcriptase and protease. Reverse transcriptase converts viral RNA into DNA, a crucial step in viral replication. Protease is responsible for cleaving viral polyproteins into functional proteins. Targeting both enzymes disrupts viral replication. Choice A is incorrect as integrase is not a main target in current therapy. Choice C is incorrect because protease is targeted along with reverse transcriptase, not integrase. Choice D is incorrect as targeting viral glycoproteins is not a main strategy in anti-HIV therapy.

Correct Answer: B

Rationale: Rationale: 1. Enteropathogenic E.coli (EPEC) adheres to the intestinal wall using bundle-forming pili. 2. EPEC produces toxins that disrupt cell structure and function, leading to diarrhea. 3. Shigella spp. invade intestinal cells, Salmonella spp. invade and multiply within cells, and Vibrio cholerae produces cholera toxin causing profuse watery diarrhea. Summary: A, C, and D choices are incorrect because they do not specifically adhere to the intestine wall and produce toxins like EPEC does.