Which of the following viruses belong to family Arenaviridae

Correct Answer: A

Rationale: The correct answer is A: Lassa virus. The rationale is as follows: 1. Lassa virus is a member of the Arenaviridae family, known for causing Lassa fever. 2. Arenaviridae family includes viruses with a segmented genome and are transmitted through rodents. 3. Crimean-Congo hemorrhagic fever virus (Choice B) belongs to the Bunyaviridae family, not Arenaviridae. 4. Rabies virus (Choice C) belongs to the Rhabdoviridae family, not Arenaviridae. 5. Epstein-Barr virus (Choice D) belongs to the Herpesviridae family, not Arenaviridae. In summary, Lassa virus is the correct choice as it aligns with the characteristics of the Arenaviridae family, while the other choices belong to different virus families.

Correct Answer: D

Rationale: The correct answer is D: complex. Bacteriophages are considered complex viruses because they have a complex structure consisting of a polyhedral head, a helical tail, and tail fibers. The head contains the viral genetic material, while the tail facilitates attachment to the host bacterial cell. This complexity distinguishes bacteriophages from simpler viruses like helical and icosahedral viruses. Helical viruses have a rod-like shape, while icosahedral viruses have a symmetrical, 20-sided structure. Enveloped viruses have a lipid bilayer envelope surrounding their capsid, which bacteriophages lack. Therefore, the unique and intricate structure of bacteriophages classifies them as complex viruses.

Correct Answer: B

Rationale: The correct answer is B: lipopolysaccharides. Endotoxins are part of the outer membrane of Gram-negative bacteria, consisting of lipid A, core polysaccharides, and O antigen. Lipopolysaccharides are known to induce strong immune responses and can cause septic shock. Proteins (choice A) are components of exotoxins, not endotoxins. Teichoic acid (choice C) is found in Gram-positive bacteria, not Gram-negative bacteria. Peptidoglycan (choice D) is a major component of bacterial cell walls but is not considered an endotoxin.

Correct Answer: B

Rationale: The correct answer is B, Streptococcus pneumoniae. This bacterium is the classic causative agent of croupous pneumonia due to its ability to infect the lungs and cause inflammation. Streptococcus pneumoniae is a common pathogen known for causing pneumonia in both adults and children. It is characterized by the presence of a capsule that helps it evade the host immune system. Choice A, Chlamydia pneumoniae, is not the correct answer as it is more commonly associated with atypical pneumonia. Choice C, Mycoplasma pneumoniae, is also associated with atypical pneumonia and not croupous pneumonia. Choice D, Staphylococcus aureus, can cause pneumonia, but it is not the classic causative agent of croupous pneumonia.

Correct Answer: A

Rationale: The correct answer is A: Tetanus. Tetanus is caused by the bacterium Clostridium tetani, commonly found in soil, dust, and animal feces. The patient's history of a stab wound increases the risk of tetanus infection as the bacterium can enter the body through the wound. Tetanus infection can lead to symptoms such as lockjaw or trismus, which are characterized by muscle stiffness and difficulty opening the mouth. This is due to the neurotoxin produced by Clostridium tetani affecting the muscles. Summary of incorrect choices: B: Brucellosis is a bacterial infection transmitted from animals to humans through consumption of unpasteurized dairy products. It does not typically manifest with symptoms of lockjaw. C: Whooping cough (Pertussis) is a respiratory infection caused by Bordetella pertussis bacteria. It presents with severe coughing fits but does not cause lockjaw. D: Anaerobic wound infection

Correct Answer: A

Rationale: Rationale: Shigella dysenteriae produces Shiga toxin, which inhibits protein synthesis by inactivating the 60S ribosomal subunit. This disrupts the translation process, leading to cell death. Escherichia coli (choice B) does not produce a toxin that inhibits protein synthesis. Clostridium tetani (choice C) produces tetanospasmin, which affects the nervous system. Staphylococcus aureus (choice D) produces toxins that cause food poisoning but do not inhibit protein synthesis.

Correct Answer: A

Rationale: The correct answer is A: Mycobacterium tuberculosis. This bacteria is responsible for causing tuberculosis because it is the specific pathogen known to infect the lungs and other parts of the body, leading to the disease. Mycobacterium tuberculosis has unique cell wall components that allow it to evade the immune system and survive in the host. Neisseria meningitidis (B) causes meningitis, not tuberculosis. Salmonella enterica (C) causes food poisoning, not tuberculosis. Streptococcus pneumoniae (D) causes pneumonia, not tuberculosis. Therefore, the correct answer is A based on the specific characteristics and pathogenicity of Mycobacterium tuberculosis.

Correct Answer: B

Rationale: The correct answer is B: Penicillin. Penicillin is the drug of first choice for treating syphilis due to its effectiveness in eradicating the bacterium Treponema pallidum, which causes syphilis. It is the most reliable treatment with well-established efficacy. Gentamicin (A), ciprofloxacin (C), and chloramphenicol (D) are not recommended for treating syphilis as they are not effective against the specific bacteria causing the infection. Penicillin remains the gold standard for syphilis treatment.

Correct Answer: C

Rationale: The correct answer is C (7.2-7.4) because most pathogenic bacteria and viruses thrive in a neutral pH environment close to 7.0. This pH range is optimal for their growth and survival. Choice A (5.0-5.5) is too acidic for most pathogens. Choice B (8.0-9.6) is too alkaline, which is not conducive for their survival. Choice D (4.2-4.4) is also too acidic and would likely inhibit the growth of pathogenic bacteria and viruses. Thus, a pH range of 7.2-7.4 provides the most suitable conditions for their proliferation.