Which of the following viruses belong to family Arenaviridae

Correct Answer: A

Rationale: The correct answer is A: Lassa virus. The rationale is as follows: 1. Lassa virus is a member of the Arenaviridae family, known for causing Lassa fever. 2. Arenaviridae family includes viruses with a segmented genome and are transmitted through rodents. 3. Crimean-Congo hemorrhagic fever virus (Choice B) belongs to the Bunyaviridae family, not Arenaviridae. 4. Rabies virus (Choice C) belongs to the Rhabdoviridae family, not Arenaviridae. 5. Epstein-Barr virus (Choice D) belongs to the Herpesviridae family, not Arenaviridae. In summary, Lassa virus is the correct choice as it aligns with the characteristics of the Arenaviridae family, while the other choices belong to different virus families.

Correct Answer: C

Rationale: The correct answer is C: Tuberculosis. Granulomas with lymphocytes and macrophages containing Virchow's cells (large cells with fat inclusions containing microorganisms) are classic findings in tuberculosis. Leprosy (A) typically presents with granulomas but with different histopathological features. Syphilis (B) does not usually form granulomas in the skin. Rhinoscleroma (D) is a chronic bacterial infection characterized by nodular lesions but does not typically involve Virchow's cells as seen in tuberculosis.

Correct Answer: A

Rationale: The correct answer is A: ethylene oxide. Ethylene oxide is a toxic, odorless gas commonly used as a sterilizing agent in healthcare settings due to its ability to effectively kill bacteria, viruses, and fungi. It is a highly reactive compound that can penetrate porous materials, making it an ideal choice for sterilization purposes. Incorrect choices: B: Carbon dioxide is not used as a sterilizing agent and is not toxic. C: Carbon monoxide is not commonly used for sterilization and has a distinct odor. D: Propane is not used for sterilization in healthcare settings and is not odorless.

Correct Answer: A

Rationale: The correct answer is A: Streptococcus pyogenes. The presence of Gram-positive cocci in chains suggests a streptococcal infection. Beta-hemolysis indicates the production of a hemolysin that lyses red blood cells, a characteristic of Streptococcus pyogenes. This bacterium is known to cause strep throat and can present with fever and sore throat. Summary: - B: Streptococcus pneumoniae is a common cause of pneumonia but typically appears as lancet-shaped cocci, not in chains. - C: Staphylococcus aureus is a gram-positive cocci in clusters, not chains, and is not typically beta-hemolytic. - D: Enterococcus faecalis is a gram-positive cocci that are part of the normal gut flora and are not typically beta-hemolytic or found in chains.

Correct Answer: D

Rationale: The correct answer is D: all of them. Malignant disease weakens the immune system, making individuals more susceptible to infections. Cytostatic therapy suppresses the immune system, increasing the risk of infections. Premature birth can lead to underdeveloped immune systems, making babies more prone to infections. Therefore, all three choices are risk factors for the development of infections. Other choices are incorrect because each individual risk factor listed contributes to an increased susceptibility to infections.

Correct Answer: D

Rationale: The correct answer is D: Q-fever. Q-fever is typically an infection that affects the lower respiratory tract, causing symptoms like pneumonia. Haemophilus influenzae pharyngitis (choice A) is an upper respiratory tract infection. Ozeana (choice B) and diphtherial croup (choice C) are not specific infections related to the lower respiratory tract. Q-fever stands out as the correct choice due to its association with lower respiratory tract infections.

Correct Answer: B

Rationale: Step-by-step rationale for why B (Gamma Interferon) is the correct answer: 1. Gamma Interferon is a type of immunomodulator that helps regulate the immune response. 2. It activates macrophages and enhances the immune system's ability to fight infections. 3. Rifampin is an antibiotic, not an immunomodulator. 4. Hexacima and Pentaxim are combination vaccines, not immunomodulators. In summary, Gamma Interferon is the correct answer as it directly influences the immune response, while the other choices are not immunomodulators.

Correct Answer: A

Rationale: The correct answer is A: Mycobacterium tuberculosis. This bacteria is responsible for causing tuberculosis because it is the specific pathogen known to infect the lungs and other parts of the body, leading to the disease. Mycobacterium tuberculosis has unique cell wall components that allow it to evade the immune system and survive in the host. Neisseria meningitidis (B) causes meningitis, not tuberculosis. Salmonella enterica (C) causes food poisoning, not tuberculosis. Streptococcus pneumoniae (D) causes pneumonia, not tuberculosis. Therefore, the correct answer is A based on the specific characteristics and pathogenicity of Mycobacterium tuberculosis.

Correct Answer: A

Rationale: The correct answer is A: Two-layer. In gram-positive bacteria, the cell envelope consists of two layers: the thick peptidoglycan layer and the cytoplasmic membrane. The peptidoglycan layer is much thicker compared to gram-negative bacteria, providing structural support and protection. The cytoplasmic membrane is located beneath the peptidoglycan layer and serves as a barrier between the cytoplasm and the external environment. The other choices are incorrect because gram-positive bacteria do have a cell envelope, it is composed of two layers, not three layers, and it is not just a single layer. Choice D is incorrect as it states that there is no cell envelope in gram-positive bacteria, which is not true.