Which of the following types of antigen presenting cells (APCs) is critical in uptake and presentation of antigen to T cells?

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NCLEX Pediatric Immunization Questions Questions

Question 1 of 5

Which of the following types of antigen presenting cells (APCs) is critical in uptake and presentation of antigen to T cells?

Correct Answer: D

Rationale: All three (macrophages, dendritic cells, B cells) are APCs critical for antigen uptake and presentation to T cells; since E is moved to D, D is correct for all.

Question 2 of 5

Which of the following best describes penicillin, a hapten?

Correct Answer: D

Rationale: Penicillin is a small hapten that requires conjugation to a carrier protein to elicit an immune response.

Question 3 of 5

Binds to various cellular receptors and to complement

Correct Answer: D

Rationale: The Fc region interacts with receptors on immune cells and complement proteins.

Question 4 of 5

Papain cleaves what region of immunoglobulin?

Correct Answer: C

Rationale: Papain cleaves above the hinge region, yielding two Fab fragments and one Fc.

Question 5 of 5

Which of the following is used to characterize antigens in complex mixtures biochemically?

Correct Answer: D

Rationale: Western blotting separates proteins by size and uses antibodies to characterize antigens biochemically in complex mixtures.

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