ATI RN
Principles of Pharmacology Questions
Question 1 of 5
Which of the following terms best defines this tolerance pattern?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
Which of the following types of drug reaction was most likely experienced by the patient?
Correct Answer: A
Rationale: The correct answer is A, Type I allergic reaction. This is because the patient developed symptoms of an anaphylactic-like reaction after exposure to vancomycin, despite not having previous exposure or antibodies to the drug. This type of reaction is typically immediate and involves the immune system's response to the drug, leading to symptoms such as hives, swelling, and difficulty breathing.
Question 3 of 5
Which of the following conditions most likely delayed the oral absorption of acetaminophen in the patient?
Correct Answer: C
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 4 of 5
Which of the following was most likely the oral bioavailability of the drug?
Correct Answer: D
Rationale: The oral bioavailability of a drug can be calculated using the formula F = AUC oral / AUC IV, where AUC is the area under the concentration-time curve. In this case, we are given the volume of distribution as 100 L and the theoretical plasma concentration at time 0 as 1 mg/L after oral administration of 200 mg. By calculating the AUC for both oral and IV routes, we can determine that the oral bioavailability is 1.0, which corresponds to option D.
Question 5 of 5
Which of the curves best depicts the log dose-response curve of that agonist when a fixed dose of a competitive α antagonist is given concomitantly?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.