ATI RN
Principles of Pharmacology Questions
Question 1 of 5
Which of the following terms best defines the cimetidine-diazepam interaction in the 46-year-old woman?
Correct Answer: B
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 2 of 5
Which of the following factors regulates the relationship between drug concentration and drug-receptor complex association and dissociation?
Correct Answer: D
Rationale: Failed to generate a rationale of 500+ characters after 5 retries.
Question 3 of 5
Which of the following can effect drug distribution inside the body?
Correct Answer: D
Rationale: Rationale: 1. Target site blood flow affects drug distribution by determining how quickly drug reaches the intended site. 2. Plasma protein binding affects distribution as only free drug is active and can reach target tissues. 3. Blood flow to the site of absorption impacts how rapidly drug is absorbed and distributed. 4. Option D is correct as both target site blood flow and blood flow to the site of absorption are crucial in drug distribution. Option A alone doesn't consider absorption, while option B focuses only on binding, neglecting absorption. Option C is specific to absorption and does not encompass target site blood flow.
Question 4 of 5
All of the following are examples of enteral routes of administration except
Correct Answer: A
Rationale: The correct answer is A: Intramuscular. Enteral routes involve administration through the gastrointestinal tract, such as oral, sublingual, and rectal. Intramuscular administration bypasses the GI tract, making it a parenteral route. Therefore, it is not an enteral route. Oral involves swallowing, sublingual is under the tongue, and rectal is through the rectum, all entering the GI tract for absorption.
Question 5 of 5
Which site of drug absorption is considered to have the largest surface area?
Correct Answer: D
Rationale: The correct answer is D: Lungs. Lungs have the largest surface area for drug absorption due to alveoli and extensive capillary network. The large surface area allows for rapid absorption of drugs into the bloodstream. Rectum, vagina, and eye have smaller surface areas and are not as efficient for drug absorption compared to the lungs. Lungs provide a direct route to the bloodstream, making them an ideal site for drug absorption.