ATI RN
Pediatric Immunization NCLEX Questions Quizlet Questions
Question 1 of 5
Which of the following TCR genetic chains contains V and J segments, similar to genes for immunoglobulin kappa and lambda light chains?
Correct Answer: D
Rationale: Gamma (γ) and alpha (α) chains contain V and J segments, analogous to light chain genes.
Question 2 of 5
MHC class I has three genes (HLA-A, HLA-B, & HLA-C). Which of the following is the correct order from most alleles (most polymorphic) to least alleles?
Correct Answer: C
Rationale: HLA-B is the most polymorphic, followed by HLA-A, then HLA-C.
Question 3 of 5
Ankylosing spondylitis
Correct Answer: A
Rationale: Ankylosing spondylitis is strongly associated with HLA-B27.
Question 4 of 5
Directly: carbohydrate, protein, lipid, nucleic acid epitopes
Correct Answer: A
Rationale: Immunoglobulins directly recognize a wide range of epitopes.
Question 5 of 5
Mutations in TAP-1 or TAP-2 may alter the function of the heterodimer TAP. Which of the following is common for patients with TAP mutations?
Correct Answer: C
Rationale: TAP mutations impair MHC Class I antigen presentation, leading to increased susceptibility to upper respiratory infections due to reduced CD8+ T cell responses.