ATI RN
Central Nervous System Stimulants and Related Drugs NCLEX Style Questions Questions
Question 1 of 5
Which of the following statements is WRONG:
Correct Answer: C
Rationale: Carbimazole treats hyperthyroidism (choice A), Levothyroxine hypothyroidism (choice B), and Propylthiouracil is pregnancy-safe (choice D), all correct. Methimazole (choice C) isn't metabolized into carbimazole; carbimazole is a prodrug for methimazole, the active form, making this wrong. This clarifies thionamide metabolism, key for therapeutic accuracy.
Question 2 of 5
A 54-year-old woman suffering from initial insomnia was prescribed a hypnotic drug that increases the activity of a major neurotransmitter system in the brain. Which of the following neurotransmitter systems was most likely involved in the therapeutic action of that drug?
Correct Answer: D
Rationale: In the treatment of insomnia, drugs that enhance GABAergic activity are commonly prescribed as they help promote relaxation and sleep. GABA is the major inhibitory neurotransmitter in the brain, and increasing its activity can lead to sedative effects, making it a likely target for a hypnotic drug.
Question 3 of 5
Which of the following statements regarding drugs of abuse is true?
Correct Answer: B
Rationale: LSD exerts its hallucinogenic effects through serotonin (5-HT) receptor modulation.
Question 4 of 5
A 14-year-old girl is brought to the emergency room as her mother observed that her daughter experienced frequent impairments of consciousness lasting for about 30 seconds. Neurological evaluation indicates 'Absence seizures'. With which of the following drugs should we start treatment?
Correct Answer: C
Rationale: Ethosuximide (choice C) treats absence seizures by reducing T-type calcium currents, ideal for brief consciousness lapses. Alprazolam (choice A), Diazepam (choice B), and Midazolam (choice D), benzodiazepines, aren't first-line for absence. Ethosuximide's specificity is key.
Question 5 of 5
Acute or chronic colchicine toxicity may be identified by which signs/symptoms?
Correct Answer: D
Rationale: Colchicine toxicity can lead to alopecia, bone marrow suppression (blood dyscrasias), and severe gastrointestinal effects such as diarrhea and vomiting.