Correct Answer: A

Rationale: The correct answer is A: Salk and Sabin vaccines are vaccines against polio. Both Salk and Sabin vaccines are indeed vaccines specifically developed to prevent polio. The Salk vaccine is an inactivated polio vaccine, while the Sabin vaccine is an oral live attenuated vaccine. Therefore, choice B is incorrect as the Sabin vaccine is live attenuated, not inactivated. Choice C is also incorrect because the Salk vaccine is inactivated, not live attenuated. Choice D is incorrect because not all statements are true; only statement A is accurate.

Correct Answer:

Rationale: Correct Answer: C: opportunists Rationale: 1. Opportunistic microorganisms cause infections only when the host's immune system is compromised. 2. They are typically harmless in healthy individuals but can become pathogenic in weakened hosts. 3. Saprophytic microorganisms are environmental decomposers, not inherently pathogenic. 4. Facultative pathogens can cause disease in both healthy and compromised hosts. 5. Obligate pathogens always cause disease regardless of the host's condition. Summary: A: Facultative pathogens can cause disease in healthy hosts. B: Saprophytes are not inherently pathogenic. D: Obligate pathogens always cause disease.

Correct Answer: A

Rationale: The correct answer is A: Francisella tularensis. This bacterium is classified as a class A bioterrorism agent due to its high virulence and potential for mass casualties. It can cause tularemia, a severe and potentially fatal disease. The other choices, Hepatitis B, E. coli, and Bacillus subtilis, are not considered class A bioterrorism agents. Hepatitis B is a virus causing liver inflammation, E. coli is a common bacterium found in the gut, and Bacillus subtilis is a beneficial bacterium used in various industries. Therefore, Francisella tularensis is the correct choice based on its high pathogenicity and bioterrorism potential.

Correct Answer: A

Rationale: The correct answer is A: Clostridium tetani. The presence of Gram-positive rods with terminal spores resembling drumsticks indicates Clostridium tetani, the causative agent of tetanus. This bacterium forms spores at one end, giving it a drumstick appearance under the microscope. Clostridium perfringens (B) and Clostridium botulinum (D) do not have terminal spores. Bacillus anthracis (C) forms spores but typically appears as a square-ended or bamboo stick shape. Therefore, based on the microscopy findings, Clostridium tetani is the most likely microorganism responsible for the wound infection.

Correct Answer: A

Rationale: The correct answer is A: Clostridium tetani. Clostridium tetani is responsible for causing tetanus by producing a neurotoxin called tetanospasmin. This neurotoxin blocks inhibitory signals in the central nervous system, leading to muscle spasms and stiffness characteristic of tetanus. Clostridium perfringens (B) causes gas gangrene, Streptococcus pyogenes (C) causes strep throat, and Escherichia coli (D) can cause gastrointestinal infections but not tetanus. Therefore, based on the specific pathogen and its mechanism of action, Clostridium tetani is the correct answer.