Which of the following statements is true regarding polio vaccines:

Correct Answer: A

Rationale: The correct answer is A: Salk and Sabin vaccines are vaccines against polio. Both Salk and Sabin vaccines are indeed vaccines specifically developed to prevent polio. The Salk vaccine is an inactivated polio vaccine, while the Sabin vaccine is an oral live attenuated vaccine. Therefore, choice B is incorrect as the Sabin vaccine is live attenuated, not inactivated. Choice C is also incorrect because the Salk vaccine is inactivated, not live attenuated. Choice D is incorrect because not all statements are true; only statement A is accurate.

Correct Answer: A

Rationale: The correct answer is A: Yersinia pestis. Y. pestis causes bubonic plague, characterized by enlarged, painful lymph nodes called buboes. The Gram-negative rods with a safety pin appearance are seen on Gram stain of Y. pestis. The other choices are incorrect because Francisella tularensis causes tularemia, not lymphadenitis with safety pin appearance. Brucella abortus causes brucellosis, which typically does not present with lymphadenitis. Clostridium botulinum causes botulism, which is not associated with lymphadenitis or safety pin appearance.

Correct Answer: D

Rationale: The correct answer is D: Viscerotropic Leishmania. The presence of crescent-shaped bodies with pointed tips, blue cytoplasm, and red nuclei is characteristic of Leishmania species. Viscerotropic Leishmania causes visceral leishmaniasis, also known as kala-azar, which affects the internal organs. Toxoplasma typically presents as tachyzoites, not crescent-shaped bodies. Plasmodium malariae is a malaria parasite with different morphology. Dermatotropic Leishmania causes cutaneous leishmaniasis, not the visceral form indicated by the morphology described in the question.

Correct Answer: A

Rationale: The correct answer is A: Haemolytic streptococci. Hemolytic streptococci are known to cause serious infections in humans, including strep throat and skin infections. These bacteria have the potential to spread rapidly and cause epidemics. Bacilli are a broad category of bacteria and not all are necessarily harmful. Micrococci are commonly found on human skin and are generally harmless. Yeast fungi are also commonly found in the environment and are not typically associated with causing epidemics. Therefore, the presence of hemolytic streptococci in the air of a pharmacy indicates a direct epidemic danger due to their pathogenic nature and potential to cause widespread infections.

Correct Answer: B

Rationale: Gas gangrene is caused by Clostridium perfringens due to its ability to produce gas in tissues leading to necrosis. Other choices are incorrect: A (C. difficile causes diarrhea), C (C. tetani causes tetanus), and D (incorrect as B is the causative agent).

Correct Answer: D

Rationale: The correct answer is D: Yersinia enterocolitica. This bacterium can contaminate foods and grow at refrigerator temperatures due to its psychrotrophic nature. Yersinia enterocolitica is known to cause foodborne illnesses even when stored at cold temperatures. Shigella sonnei is a human pathogen transmitted through fecal-oral route, Campylobacter jejuni is typically found in poultry and causes food poisoning, and E. coli can cause foodborne illnesses but does not grow well at refrigerator temperatures.

Correct Answer: A

Rationale: The correct answer is A: Pertussis bacillus. The symptoms described - elevated temperature and typical cough - are indicative of whooping cough, caused by Bordetella pertussis. By inoculating mucus from the nasopharynx on agar, the doctor is trying to isolate the causative agent, which is likely to be Pertussis bacillus. Summary of other choices: B: Pfeiffer's bacillus (Haemophilus influenzae): Unlikely as symptoms do not match. C: Listeria: Unlikely as it typically causes foodborne illness, not respiratory infections. D: Klebsiella: Unlikely as it is more commonly associated with pneumonia in immunocompromised individuals.

Correct Answer: C

Rationale: Step 1: Anthrax causative agent is Bacillus anthracis, which forms spores. Step 2: Spores are highly resistant structures that can survive for a long time. Step 3: These spores can germinate into active bacteria when conditions are favorable. Step 4: The presence of spores in the powder makes it dangerous even long after being mailed. Summary: A: Incorrect - Anthrax does not form a protein capsule. B: Incorrect - Anthrax does not form a polysaccharide capsule. C: Correct - Anthrax forms spores that are highly resistant. D: Incorrect - Anthrax does not form flagella.

Correct Answer: C

Rationale: The correct answer is C: Thick peptidoglycan layer. Gram-positive bacteria have a thick peptidoglycan layer in their cell wall, which retains the crystal violet stain in the Gram staining process, leading to a purple color. This thick layer is a defining characteristic of Gram-positive bacteria. Rationale: A: Thin peptidoglycan layer is incorrect because Gram-positive bacteria have a thick peptidoglycan layer. B: Presence of an outer membrane is incorrect because Gram-positive bacteria lack an outer membrane. D: Presence of lipopolysaccharides is incorrect because lipopolysaccharides are typically found in the outer membrane of Gram-negative bacteria, not Gram-positive bacteria.