ATI RN
Immune System Exam Questions Questions
Question 1 of 5
Which of the following statements is correct about splenic sinusoids?
Correct Answer: B
Rationale: Splenic sinusoids are lined with elongated endothelial cells with large spaces ; Kupffer cells are in liver , stave cells line sinusoids (C is misphrased), basement membranes are discontinuous .
Question 2 of 5
What is the function of TAP1 and TAP2 proteins?
Correct Answer: B
Rationale: TAP1/2 transport cytosolic peptides into the ER for MHC I loading ; invariant chain and CLIP are MHC II-related.
Question 3 of 5
What cytokine does a Th1 cell produce that influences B cells during class switching to produce IgG3?
Correct Answer: C
Rationale: IFN-γ from Th1 cells drives IgG3 class switching ; IL-4 favors IgE, TNF and IL-2 have other roles.
Question 4 of 5
How do NK cells recognize healthy cells?
Correct Answer: B
Rationale: NK cells spare healthy cells with MHC I ; opsonization is phagocytic, editing/selection (C, D) are lymphocyte processes.
Question 5 of 5
Substances called the are capable of directly inhibiting DNA synthesis
Correct Answer: B
Rationale: Interferons inhibit viral DNA/RNA synthesis; antibodies , complement , and histamines have other roles.