Which of the following statements is correct?

Correct Answer: C

Rationale: Rationale: MAO-A primarily metabolizes norepinephrine and serotonin, as these neurotransmitters are broken down in the synaptic cleft. MAO-B mainly metabolizes dopamine. Thus, choice C is correct. Choices A, B, and D are incorrect because they inaccurately assign the neurotransmitters to MAO-A and MAO-B, leading to an incorrect understanding of their functions.

Correct Answer: B

Rationale: The correct answer is B: Clozapine. Clozapine is a dibenzodiazepine derivative, specifically a dibenzodiazepine antipsychotic agent. It is known for its efficacy in treating treatment-resistant schizophrenia. Fluphenazine (A) is a phenothiazine antipsychotic, Risperidone (C) is a benzisoxazole antipsychotic, and Droperidol (D) is a butyrophenone antipsychotic. These other options belong to different classes of antipsychotic agents and are not dibenzodiazepine derivatives like Clozapine.

Correct Answer: C

Rationale: The correct answer is C: Mirtazapine. Mirtazapine is known to have significant alpha2-adrenoreceptor antagonism, leading to increased release of norepinephrine and serotonin. This mechanism of action helps improve mood and alleviate depression symptoms. Amitriptyline, Nefazodone, and Doxepin do not have significant alpha2-adrenoreceptor antagonism. Amitriptyline primarily works by inhibiting the reuptake of norepinephrine and serotonin, Nefazodone primarily inhibits serotonin reuptake, and Doxepin primarily blocks histamine receptors.

Correct Answer: B

Rationale: The correct answer is B: Triazolam. Triazolam has a short elimination half-life, around 2-5 hours, due to its rapid metabolism. Quazepam (choice A) has a longer elimination half-life, around 39 hours. Diazepam (choice C) has a longer elimination half-life, around 20-100 hours. Clorazepate (choice D) has a longer elimination half-life, around 36-200 hours. In summary, Triazolam is the correct answer as it has the shortest elimination half-life compared to the other benzodiazepines listed.

Correct Answer: D

Rationale: The correct answer is D because industrial solvent inhalation can cause quick intoxication due to the rapid absorption into the bloodstream, euphoria and a relaxed feeling due to the effects on the central nervous system, disorientation, slow passage of time, and hallucinations due to the impact on brain function. Choices A, B, and C all reflect different aspects of the effects of industrial solvent inhalation on the body and mind, making them incorrect individually. The combination of these effects, as stated in option D, accurately represents the comprehensive impact of inhalation of industrial solvents.