Which of the following statements concerning vitamin B12 (cyanocobalamin) functions are true:

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Cardiovascular Drugs Pharmacology NCLEX Questions Questions

Question 1 of 5

Which of the following statements concerning vitamin B12 (cyanocobalamin) functions are true:

A. Active functional form is pyridoxal phosphate, which is an essential coenzyme for transamination and decarboxylation of amino acids in more than 50 different enzyme systems B. Essential constituent of coenzyme A, the important coenzyme for acyl transfer in the TCA cycle and de novo fatty acid synthesis C. Coenzyme for numerous metabolic reaction, including transformation of methylamlonyl CoA to succinyl CoA in the metabolism of propionate; DNA synthesis (acts in concert with folic acid); transmethylation e.g. methionine synthesis from homocysteine D. An extremely important antioxidant, which protects cell membrane lipids from peroxidation by breaking the chain reaction of free radical formation to which polyunsaturated fatty acids are particularly vulnerable

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

Action of vitamin D3 is:

A. Increased calcium and phosphate absorption by 1,25-dihydroxyvitamin D3 B. Calcium and phosphate excretion may be decreased by 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 C. Increased calcium and phosphate resorption by 1,25-dihydroxyvitamin D3; bone formation may be increased by 25,24-dihydroxyvitamin D3 D. All of the above

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Which of the following statements refers to gallium nitrate:

A. It is approved by the FDA for the management of hypercalcemia of malignancy B. This drug acts by inhibiting bone resorption C. Because of potential nephrotoxicity, patients should be well-hydrated and have good renal output before starting the infusion D. All of the above

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

General principles of anti-infective therapy are:

A. Clinical judgment of microbiological factors B. Definitive identification of a bacterial infection and the microorganism’s susceptibility C. Optimal route of administration, dose, dosing frequency and duration of treatment D. All of the above

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

All of the following drugs demonstrate a fungicidal effect, EXCEPT:

A. Terbinafin B. Amfotericin B C. Ketoconazole D. Myconazol

Correct Answer: C

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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