Which of the following statements concerning pyridoxine (vitamin B6) functions are true:

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Pharmacology Across the Lifespan Questions

Question 1 of 5

Which of the following statements concerning pyridoxine (vitamin B6) functions are true:

A. Active functional form is pyridoxal phosphate, which is an essential coenzyme for transamination and decarboxylation of amino acids in more than 50 different enzyme systems B. Active group of the coenzymes nicotinamide-adenine dinucleotide (NAD) and nicotinamide-adenine dinucleotide phosphate (NADP) C. Essential constituent of flavoproteins, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD) D. An extremely important antioxidant, which protects cell membrane lipids from peroxidation by breaking the chain reaction of free radical formation to which polyunsaturated fatty acids are particularly vulnerable

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

Which of the following antienzymes is a beta-lactamase inhibitor?

A. Clavulanic acid B. Sulbactam C. Tazobactam D. All of the above

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

Very low density lipoprotein (VLDL) is:

A. A lipoprotein containing a very large proportion of lipids to protein and carrying most cholesterol from the liver to the tissues B. A lipoprotein that contains relatively high amounts of cholesterol and is associated with an increased risk of atherosclerosis and coronary artery disease. It is also called beta-lipoprotein C. A lipoprotein that contains relatively small amounts of cholesterol and triglycerides and is associated with a decreased risk of atherosclerosis and coronary artery disease. It is also called alpha-lipoprotein D. Large lipoprotein particle that is created by the absorptive cells of the small intestine. It transports lipids to adipose tissue where they are broken down by lipoprotein lipase

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

Clofibrate (Atromid-S) is the drug of choice for treatment of broad-beta hyperlipidemia (type III). This consideration is:

A. TRUE B. FALSE C. All of the above D. None of the above

Correct Answer: B

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

Lovastatin (Mevacor) plus a bile-acid binding resin causes regression of coronary lesions in about one third of treated patients. This consideration is:

A. TRUE B. FALSE C. All of the above D. None of the above

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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