Which of the following statements concerning biotin functions are true:

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Pharmacology Across the Lifespan ATI Quizlet Questions

Question 1 of 5

Which of the following statements concerning biotin functions are true:

A. Active functional form is pyridoxal phosphate, which is an essential coenzyme for transamination and decarboxylation of amino acids in more than 50 different enzyme systems B. Essential constituent of coenzyme A, the important coenzyme for acyl transfer in the TCA cycle and de novo fatty acid synthesis C. An extremely important antioxidant, which protects cell membrane lipids from peroxidation by breaking the chain reaction of free radical formation to which polyunsaturated fatty acids are particularly vulnerable D. Coenzyme for several reactions involving CO2 fixation into various compounds e.g. acetyl CoA to malonyl CoA (acetyl CoA carboxylase) – initial step in de novo fatty acid synthesis; propionyl CoA to methylmalonyl CoA (propionyl CoA carboxylase), pyruvate to oxaloacetate (pyruvate carboxylase)

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 2 of 5

Which of the following antienzymes is an aldehyde dehydrogenase inhibitor?

A. Tazobactam B. Sulbactam C. Aminocaproic acid D. Disulfiram

Correct Answer: D

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 3 of 5

High-density lipoprotein (HDL) is:

A. A lipoprotein that contains relatively small amounts of cholesterol and triglycerides and is associated with a decreased risk of atherosclerosis and coronary artery disease. It is also called alpha-lipoprotein B. A lipoprotein containing a very large proportion of lipids to protein and carrying most cholesterol from the liver to the tissues C. A lipoprotein that contains relatively high amounts of cholesterol and is associated with an increased risk of atherosclerosis and coronary artery disease. It is also called beta-lipoprotein D. Large lipoprotein particle that is created by the absorptive cells of the small intestine. It transports lipids to adipose tissue where they are broken down by lipoprotein lipase

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 4 of 5

Probucol (Lorelco) appears to increase clearance of LDL cholesterol by a non-receptor mediated mechanism. This consideration is:

A. TRUE B. FALSE C. All of the above D. None of the above

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

Question 5 of 5

Selected liver and muscle enzymes should be monitored during the use of any cholesterol synthesis inhibitors because of possible toxic effects. This consideration is:

A. TRUE B. FALSE C. All of the above D. None of the above

Correct Answer: A

Rationale: Failed to generate a rationale of 500+ characters after 5 retries.

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