Which of the following statement is true regarding the treatment of Parkinson's Disease?

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Safety Pharmacology Across the Lifespan ATI Quizlet Questions

Question 1 of 5

Which of the following statement is true regarding the treatment of Parkinson's Disease?

Correct Answer: B

Rationale: Step-by-step rationale for why choice B is correct: 1. Levodopa is the most effective medication for managing the motor symptoms of Parkinson's disease. 2. Carbidopa is often combined with Levodopa to enhance its effectiveness and reduce side effects. 3. The combination of Levodopa and Carbidopa is a standard and widely accepted treatment for Parkinson's disease. 4. Other choices are incorrect: A - Deep brain stimulation is not used to wean off patients from Levodopa; C - Amantadine is not typically used as a monotherapy for Parkinson's disease; D - Dopamine is not a medication but a neurotransmitter, and Levodopa is the preferred treatment over dopamine.

Question 2 of 5

The nurse administers 50 mg of a drug at 6:00 AM that has a half-life of 8 hours. What time will it be when 25 mg of the drug has been eliminated from the body?

Correct Answer: C

Rationale: To determine when 25 mg of the drug will be eliminated, we first calculate the time it takes for half the initial dose to be eliminated, which is 8 hours. So, by 2:00 PM (8 hours after administration), 25 mg will be eliminated. This is because half of the initial 50 mg (25 mg) would have been metabolized by then. Therefore, the correct answer is C. Choice A (8:00 AM) is incorrect because it is too early for 25 mg to be eliminated. Choice B (11:00 AM) is incorrect because it is only 5 hours after administration, not enough time for 25 mg to be eliminated. Choice D (6:00 PM) is incorrect because it is too late, as 25 mg would have been eliminated by 2:00 PM.

Question 3 of 5

Which of the following drugs would be appropriate for systemic antifungal treatment of this patient?

Correct Answer: B

Rationale: The correct answer is B: Caspofungin. This drug is appropriate for systemic antifungal treatment as it inhibits the synthesis of beta-glucan in fungal cell walls. It is effective against a broad spectrum of fungal infections. Amphotericin B (A) is also a systemic antifungal but is associated with more severe side effects. Piperacillin (C) is an antibiotic not used for antifungal treatment. Metronidazole (D) is an antiprotozoal and antibiotic, not effective against systemic fungal infections.

Question 4 of 5

Which of the following pairs of drugs were most likely given?

Correct Answer: D

Rationale: The correct answer is D: Amphotericin B and fluconazole. Amphotericin B is an antifungal medication used for severe fungal infections, while fluconazole is commonly used for less severe fungal infections. The combination of these two drugs would be most likely given to treat a severe fungal infection that requires immediate and potent treatment. A: Amphotericin B and terbinafine - Terbinafine is primarily used to treat fungal infections of the skin and nails, not severe systemic fungal infections. B: Caspofungin and griseofulvin - Griseofulvin is used to treat superficial fungal infections like ringworm, while caspofungin is used for systemic fungal infections. C: Caspofungin and metronidazole - Metronidazole is an antibiotic used to treat bacterial and parasitic infections, not fungal infections.

Question 5 of 5

Which of the following drugs is used to treat infections caused by Plasmodium species (malaria)?

Correct Answer: A

Rationale: Step 1: Chloroquine is a known antimalarial drug that targets Plasmodium species by inhibiting their ability to replicate within red blood cells. Step 2: Amoxicillin is an antibiotic effective against bacteria, not parasites like Plasmodium. Step 3: Levofloxacin and Ciprofloxacin are also antibiotics that target bacterial infections, not malaria caused by Plasmodium species.

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